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Benzenesulfonamide, N-[bis(4-methoxyphenyl)phenylmethyl]-4-bromo-2-fluoro- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

491876-10-9

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491876-10-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 491876-10-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,1,8,7 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 491876-10:
(8*4)+(7*9)+(6*1)+(5*8)+(4*7)+(3*6)+(2*1)+(1*0)=189
189 % 10 = 9
So 491876-10-9 is a valid CAS Registry Number.

491876-10-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-N-(4,4'-dimethoxytrityl)-2-fluorobenzenesulfonamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:491876-10-9 SDS

491876-10-9Relevant academic research and scientific papers

Convenient Approach to 3,4-Diarylisoxazoles Based on the Suzuki Cross-Coupling Reaction

Dileep Kumar,Ho, ManKit M.,Leung, Jennifer M.,Toyokuni, Tatsushi

, p. 1146 - 1151 (2007/10/03)

The Suzuki cross-coupling reaction was found effective for rapid access to a series of 3,4-diarylisoxazoles of pharmacological interest. The efficiency of this approach was demonstrated by the synthesis of the highly potent COX-2-selective inhibitor, 4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide (valdecoxib), and its analogues. Thus, the coupling reaction between (3-aryl-5-methyl-4-isoxazolyl)boronic acids, prepared in situ from the corresponding bromides using triisopropyl borate, and aryl bromides containing a 4-sulfonamide or 4-methylsulfonyl group under the standard conditions [Pd(PPh3)4, Na2CO3, EtOH-H2O, reflux] yielded the target 3,4-diarylisoxazoles in good yields.

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