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5-(phenoxymethyl)-3-phenyl-1,2,4-oxadiazole is a chemical compound with the molecular formula C15H11N2O2. It is a derivative of 1,2,4-oxadiazole, a heterocyclic organic compound consisting of a five-membered ring with two oxygen atoms and one nitrogen atom. The molecule features a phenyl group (C6H5) attached to the 3-position of the oxadiazole ring and a phenoxymethyl group (C6H5-O-CH2) at the 5-position. 5-(phenoxymethyl)-3-phenyl-1,2,4-oxadiazole is known for its potential applications in various fields, such as pharmaceuticals, agrochemicals, and materials science, due to its unique chemical structure and properties. It can be synthesized through various methods, including condensation reactions involving phenyl hydrazine and phenyl esters, and is often used as a building block for the development of new compounds with specific biological activities or material properties.

4927-16-6

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4927-16-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4927-16-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,2 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4927-16:
(6*4)+(5*9)+(4*2)+(3*7)+(2*1)+(1*6)=106
106 % 10 = 6
So 4927-16-6 is a valid CAS Registry Number.

4927-16-6Downstream Products

4927-16-6Relevant academic research and scientific papers

Facile room-temperature assembly of the 1,2,4-oxadiazole core from readily available amidoximes and carboxylic acids

Sharonova, Tatyana,Pankrat'eva, Vitalina,Savko, Polyna,Baykov, Sergey,Shetnev, Anton

, p. 2824 - 2827 (2018/06/13)

A one-pot ambient-temperature procedure for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles from amidoximes and carboxylic acids under superbase-promoted conditions is reported.

Parallel synthesis of 1,2,4-oxadiazoles from carboxylic acids using an improved, uronium-based, activation

Poulain, Rébecca F.,Tartar, André L.,Déprez, Benot P.

, p. 1495 - 1498 (2007/10/03)

We describe the synthesis of 1,2,4-oxadiazoles from carboxylic acids and amidoximes using 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) as an activating agent of the carboxylic acid function for the O-acylation step. This method was used for the synthesis of a library of 24 1,2,4-oxadiazoles.

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