4927-53-1

Basic information

• Product Name: Ethanone, 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-
• Synonyms: 3',4,4'-Trimethoxy-desoxybenzoin;3,4-dimethoxybenzyl 4-methoxyphenyl ketone;4,3',4'-trimethoxy-deoxybenzoin;2-(3,4-dimethoxyphenyl)-4'-methoxyacetophenone;4,3',4'-Trimethoxy-desoxybenzoin
• CAS NO: 4927-53-1
• Molecular Formula: C17H18O4
• Molecular Weight: 286.328
• Mol File: 4927-53-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-(4927-53-1)
• EPA Substance Registry System: Ethanone, 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-(4927-53-1)

Safety Data

• Hazardous Substances Data: 4927-53-1(Hazardous Substances Data)

Usage

General Description

Ethanone, 2-(3,4-dimethoxyphenyl)-1-(4-methoxyphenyl)-, also known as 2,3,4-trimethoxyacetophenone, is a chemical compound used as a flavoring agent and fragrance ingredient. It belongs to the class of acetophenones, which are organic compounds containing a ketone group attached to a benzene ring. This specific compound is characterized by having two methoxy groups attached to the third and fourth positions of the phenyl ring, and one methoxy group attached to the fourth position of the phenyl ring. It is commonly used in the production of perfumes, soaps, and other personal care products for its sweet, floral, and woody aroma. Additionally, it has potential applications in the pharmaceutical and food industries as a flavoring and aromatic agent.

Upstream product

• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 100-66-3 methoxybenzene 
• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 

Downstream Products

• 61350-37-6 2-(4,5-Dimethoxy-2-nitro-phenyl)-1-(4-methoxy-phenyl)-butan-1-one 
• 61350-22-9 2-(4,5-Dimethoxy-2-nitro-phenyl)-1-(4-methoxy-phenyl)-butan-1-ol 
• 61350-38-7 Buten ⁽²⁰⁾ 
• 87203-62-1 1-(4-methoxyphenyl)-2-(3,4-dimethoxyphenyl)ethylamine 
• 86633-37-6 2'-(ethoxycarbonyl)-4,3',4'-trimethoxydeoxybenzoin 
• 73867-59-1 2-acetoxy-1-(4-methoxyphenyl)-2-(3,4-dimethoxyphenyl)ethanone 
• 102520-89-8 Acetic acid 2-acetoxy-5-{1-[1-(4-acetoxy-phenyl)-1-phenyl-meth-(E)-ylidene]-propyl}-phenyl ester 
• 102520-88-7 Acetic acid 2-acetoxy-5-{1-[1-(4-acetoxy-phenyl)-1-phenyl-meth-(Z)-ylidene]-propyl}-phenyl ester 

Relevant articles and documents

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C-H Functionalization Cascades

Structurally complex benzo- and spiro-fused N-polyheterocycles can be accessed via intramolecular Pd(0)-catalyzed alkene 1,2-aminoarylation reactions. The method uses N-(pentafluorobenzoyloxy)carbamates as the initiating motif, and this allows aza-Heck-type alkene amino-palladation in advance of C-H palladation of the aromatic component. The chemistry is showcased in the first total synthesis of the complex alkaloid (+)-pileamartine A, which has resulted in the reassignment of its absolute stereochemistry.

Further studies on the application of vinylogous amides and β-halovinylaldehydes to the regiospecific synthesis of unsymmetrical, polyfunctionalized 2,3,4- and 1,2,3,4- substituted pyrroles

Highly functionalized pyrroles with appropriate regiochemical functionality represent an important class of marine natural products and potential drug candidates. We describe herein a detailed study of the reaction of α-aminoacid esters with vinylogous amides and also β-halovinylaldehydes for the regiospecific synthesis of 2,3,4-trisubstituted and 1,2,3,4-tetrasubstituted pyrroles. Since the vinylogous amides and β-halovinylaldehydes are readily available precursors, rapid access to a wide variety of unsymmetrically substituted pyrroles is accomplished via this methodology.

α-(4-Tolyl)dopamine, derivatives and analogues; synthesis and pharmacological screening

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