4929-52-6Relevant academic research and scientific papers
Chemoselective Chan-Lam Coupling Reactions between Benzimidazoline-2-thiones and Arylboronic Acids
Liu, Xing,Dong, Zhi-Bing
, p. 11524 - 11532 (2019/10/02)
An efficient Chan-Lam-type methodology for the selective synthesis of S-arylbenzimidazoles and N,S-diarylbenzimidazoles was developed. The selectivity was controlled by varying the amount of the catalyst Cu(OAc)2·H2O, temperature, an
Ligand-Free CuI-Catalyzed Chemoselective S-Arylation of 2-Mercaptobenzimidazole with Aryl Iodides
Tan, Bryan Yong-Hao,Teo, Yong-Chua
supporting information, p. 2056 - 2060 (2018/09/18)
A practical and efficient strategy for the chemoselective C-S cross-coupling of 2-mercaptobenzimidazole derivatives with a range of substituted aryl iodides is described. Under the optimized conditions of 5 mol% CuI and 100 °C, a variety of S-arylated products were obtained in good to excellent yields (up to 92 %) without the need for assisting ligands.
An efficient method to access 2-substituted benzimidazoles under solvent-free conditions
Lan, Ping,Romero, F. Anthony,Malcolm, Threshia S.,Stevens, Benjamin D.,Wodka, Dariusz,Makara, Gergely M.
, p. 1910 - 1914 (2008/09/19)
An expeditious method to access 2-substituted benzimidazoles was developed. Both aromatic (phenols, anilines, and thiophenols) and alkyl nucleophiles (amines and thiols) react with 2-methylsulfonyl benzimidazole under solvent-free conditions to generate a variety of 2-substituted benzimidazoles.
