493-75-4 Usage
Originator
Camoform HCl,Parke Davis,US,1956
Uses
Anti-amebic.
Manufacturing Process
Paraformaldehyde (7.59) (0.25mol) and 18.3 g (0.25 mol) of diethylamine are
mixed in 25 cc of alcohol and warmed until a clear solution is obtained. The solution is cooled and mixed with 26.6 g (0.10 mol) of 3,3'-diallyl-4,4'-
biphenol in 25 cc of alcohol. After standing several hours, the solution is
warmed for one hour on the steam bath, allowing the alcohol to boil off. The
residue is then taken up in ether and water, the ether layer separated and
washed with 2% sodium hydroxide solution and finally with water. The washed
ether solution is dried over solid potassium carbonate, and filtered. After
acidifying with alcoholic hydrogen chloride, the ether is distilled off and the
alcoholic residue diluted with an equal volume of acetone. The crystalline
hydrochloride is filtered off, triturated with alcohol, diluted with several
volumes of acetone, filtered and dried; MP 209°-210°C.
Check Digit Verification of cas no
The CAS Registry Mumber 493-75-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 3 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 493-75:
(5*4)+(4*9)+(3*3)+(2*7)+(1*5)=84
84 % 10 = 4
So 493-75-4 is a valid CAS Registry Number.
InChI:InChI=1/C28H40N2O2/c1-7-13-21-15-23(17-25(27(21)31)19-29(9-3)10-4)24-16-22(14-8-2)28(32)26(18-24)20-30(11-5)12-6/h7-8,15-18,31-32H,1-2,9-14,19-20H2,3-6H3
493-75-4Relevant academic research and scientific papers
Schlosser, Manfred,Michel, Dominique,Croft, Simon L.
, p. 591 - 593 (1996)
In a successful attempt to amplify the pharmacological activity of the antimalarial bialamicol, substituents have been introduced in the 2-position of the allyl side chains. 2-Fluoroallyl bromide, a versatile C3F building block, is described for the first time.
