4942-70-5

Usage

InChI:InChI=1/C13H15N3O/c1-10-12(9-15(2)3)13(17)16(14-10)11-7-5-4-6-8-11/h4-9H,1-3H3/b12-9+

Upstream product

• 89-25-8 edaravone 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 
• 68-12-2 N,N-dimethyl-formamide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 57464-99-0 4-[((Z)-3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-4-ylidenemethyl)-amino]-N-thiazol-2-yl-benzenesulfonamide 
• 57465-01-7 N-(5-methyl-isoxazol-3-yl)-4-[(3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-4-ylidenemethyl)-amino]-benzenesulfonamide 
• 74414-04-3 Sodium; 4-((E)-2-cyano-2-ethoxycarbonyl-vinyl)-5-methyl-2-phenyl-2H-pyrazol-3-olate 
• 97227-12-8 potassium salt of 1-phenyl-3-methyl-4-cyanomethylene-5-pyrazolone 
• 97227-12-8 1-phenyl-3-methyl-4-cyanomethylene-5-pyrazolone potassium salt 
• 107486-76-0 mononitrile of (1-phenyl-3-methyl-5-oxo-4-pyrazolylidene)succinic acid 
• 97227-13-9 potassium salt of the mononitrile of (1-phenyl-3-methyl-5-oxo-4-pyrazolylidene)malonic acid 
• 4702-90-3 1-phenyl-3-methyl-4-(1-phenyl-3-methyl-5-oxo-4-pyrazolylidene)methylene-5-pyrazolone 
• 804437-23-8 (3-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-4-ylmethylene)-malononitrile 
• 74413-97-1 5-Cyano-3-methyl-6-oxo-1-phenyl-2H-pyrano<2,3-c>pyrazol 
• 74413-99-3 4-(E,2-Carboxamido-2-cyanoethenyl)-5-ethoxy-3-methyl-1-phenylpyrazol 
• 74414-03-2 Sodium; 4-((E)-2-carbamoyl-2-cyano-vinyl)-5-methyl-2-phenyl-2H-pyrazol-3-olate 
• 107486-80-6 1-phenyl-3-methyl-4-dimethylaminomethylene-5-pyrazolone sodium salt 
• 1242681-80-6 3,6,8-trimethyl-1-phenyl-1H-pyrazolo[4',3':5,6]pyrido[2,3-d]pyrimidine-5,7(6H,8H)-dione 

Relevant academic research and scientific papers

Design, synthesis, and biological evaluation of indolylidinepyrazolones as potential anti-bacterial agents

A series of indolylidinepyrazolones were synthesized using a simple, green, and effective route and evaluated as anti-bacterial agents. The compounds were further studied via structure-guided docking study. One of the compounds exhibiting H-bonding interactions with conserved residue Arg144 turned out to be the most potent compound of the series. The minimum inhibitory concentration values ranged from 50 to 25 μg/mL against Staphylococcus aureus in their anti microbial evaluation.

A convenient route for the synthesis of some new Bi-and triheterocondensed uracils

Some bifunctional heterocyclic systems having vicinal chlorocyano, chloroacetyl, and chloro-ethoxycarbonyl groups in their structures reacted with 6-amino-1,3-dimethyluracil to afford novel triheterocyclic systems having a pyrimidinedione moiety. Enaminones and a-cyanocinnamic acid derivatives in this reaction gave pyrido[2,3-d]pyrimidinediones. The antimicrobial activity of some new synthesized triheterocyclic systems was studied. 2010 Springer Science+Business Media, Inc.

Proton Magnetic Resonance Studies of International Rotation, 10. Conformation and Stereodynamics of Dipolar Cyclic Enamines and Hydrazones

2-Aminomethylene and 2-hydrazono derivatives 1-6 of carbocyclic and heterocyclic 1,3-dicarbonyl compounds which may form up to four rotational diastereoisomers were investigated by 1H and 13C NMR spectroscopy.The isomeric composition