4943-67-3

Basic information

• Product Name: 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE
• Synonyms: 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE;5-METHYL-4-AZAINDOLE;1H-Pyrrolo[3,2-b]pyridine, 5-Methyl-
• CAS NO: 4943-67-3
• Molecular Formula: C8H8N2
• Molecular Weight: 132.16252
• Product Categories: Heterocycles series
• Mol File: 4943-67-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 268.709 °C at 760 mmHg
• Flash Point: 117.984 °C
• Appearance: /
• Density: 1.187 g/cm³
• Vapor Pressure: 0.013mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE(4943-67-3)
• EPA Substance Registry System: 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE(4943-67-3)

Safety Data

• Hazardous Substances Data: 4943-67-3(Hazardous Substances Data)

Usage

General Description

5-Methyl-1H-pyrrolo[3,2-b]pyridine is a chemical compound consisting of a pyrrolopyridine ring system with a methyl group attached to the 5-position of the pyrrole ring. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its unique structure and reactivity. 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE has also been studied for its potential biological activities, including as an anti-inflammatory and anticancer agent. Its versatile nature and potential therapeutic applications make it a valuable target for chemical and pharmaceutical research.

InChI:InChI=1/C8H8N2/c1-6-2-3-7-8(10-6)4-5-9-7/h2-5,9H,1H3

Upstream product

• 54173-21-6 N-(2,6-dimethyl-[3]pyridyl)-formamide 
• 541-16-2 t-butyl malonate 
• 3430-33-9 2,6-dimethylpyridin-3-amine 
• 15513-52-7 3-nitro-2,6-lutidine 
• 1227268-74-7 5-bromo-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine 
• 1000341-51-4 5-bromo-1H-pyrrolo[3,2-b]pyridine 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 65156-94-7 5-chloro-1H-pyrrolo[3,2-b]pyridine 
• 823-96-1 Trimethylboroxine 
• 1420070-26-3 6-chloro-2-[(E)-2-ethoxyvinyl]pyridin-3-amine 
• 400777-06-2 6-chloro-2-iodopyridin-3-amine 

Downstream Products

• 1000343-73-6 3-bromo-5-methyl-1H-pyrrolo[3,2-b]pyridine 
• 1082208-17-0 7-chloro-5-methyl-1H-pyrrolo[3,2-b]pyridine 

Relevant articles and documents

Pyridine N-oxidation derivative as well as preparation method and application thereof

The invention relates to a pyridine N-oxidation derivative as well as a preparation method and an application thereof, in particular to a compound shown in a general formula (I), a preparation methodof the compound, pharmaceutical composition containing the compound and an application of the compound as a BRD4 inhibitor in treating related diseases such as cancer, inflammation, chronic liver diseases, diabetes, cardiovascular diseases, AIDS and the like, wherein in the general formula (I), all substituent groups are the same as definitions in the description.

4-AZAINDOLE DERIVATIVES

4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

NEW CRTH2 ANTAGONISTS

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.