4943-67-3

Usage

Uses

Used in Pharmaceutical Industry:
5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE is used as a key building block for the synthesis of various pharmaceuticals due to its unique structure and reactivity. Its incorporation into drug molecules can potentially enhance their therapeutic effects and properties.
Used in Agrochemical Industry:
In the agrochemical industry, 5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE serves as a crucial component in the development of new agrochemicals. Its unique chemical properties allow for the creation of innovative products with improved efficacy and selectivity in crop protection.
Used in Anti-inflammatory Applications:
5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE is studied for its potential as an anti-inflammatory agent. Its ability to modulate inflammatory pathways and reduce inflammation makes it a promising candidate for the development of new anti-inflammatory drugs.
Used in Anticancer Applications:
5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE has been investigated for its potential as an anticancer agent. Its unique structure and reactivity may contribute to the development of novel cancer therapies, offering new treatment options for patients.
Used in Chemical Research:
5-METHYL-1H-PYRROLO[3,2-B]PYRIDINE is utilized in chemical research for the exploration of its versatile nature and potential applications. Its unique properties and reactivity make it an interesting target for the development of new chemical compounds and materials.

InChI:InChI=1/C8H8N2/c1-6-2-3-7-8(10-6)4-5-9-7/h2-5,9H,1H3

Upstream product

• 54173-21-6 N-(2,6-dimethyl-[3]pyridyl)-formamide 
• 15513-52-7 3-nitro-2,6-lutidine 
• 541-16-2 t-butyl malonate 
• 1227268-74-7 5-bromo-1-(phenylsulfonyl)-1H-pyrrolo[3,2-b]pyridine 
• 1000341-51-4 5-bromo-1H-pyrrolo[3,2-b]pyridine 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 65156-94-7 5-chloro-1H-pyrrolo[3,2-b]pyridine 
• 823-96-1 Trimethylboroxine 
• 1420070-26-3 6-chloro-2-[(E)-2-ethoxyvinyl]pyridin-3-amine 
• 400777-06-2 6-chloro-2-iodopyridin-3-amine 
• 3430-33-9 2,6-dimethylpyridin-3-amine 

Downstream Products

• 1000343-73-6 3-bromo-5-methyl-1H-pyrrolo[3,2-b]pyridine 
• 1082208-17-0 7-chloro-5-methyl-1H-pyrrolo[3,2-b]pyridine 

Relevant academic research and scientific papers

Pyridine N-oxidation derivative as well as preparation method and application thereof

The invention relates to a pyridine N-oxidation derivative as well as a preparation method and an application thereof, in particular to a compound shown in a general formula (I), a preparation methodof the compound, pharmaceutical composition containing the compound and an application of the compound as a BRD4 inhibitor in treating related diseases such as cancer, inflammation, chronic liver diseases, diabetes, cardiovascular diseases, AIDS and the like, wherein in the general formula (I), all substituent groups are the same as definitions in the description.

4-Azaindole Derivatives

4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

4-AZAINDOLE DERIVATIVES

4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

New CRTh2 antagonists

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.

NEW CRTH2 ANTAGONISTS

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.

Pharmaceutically active 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines

Compounds of the formula STR1 wherein one of A, B, D and E is N and the remaining three atoms are C; R1 and R2 are independently selected from hydrogen and C1 to C6 alkyl; and R3, R4, R5 and R6 are independently selected from hydrogen, halogen, hydroxy, C1 -C6 alkyl, C1 -C8 alkoxy, phenyl-C1 -C6 alkoxy, phenoxy --NR7 R8 wherein R7 and R8 are independently selected from hydrogen, C1 -C8 alkyl, C1 -C6 alkanoyl and COOR9 wherein R9 is hydrogen or C1 -C6 alkyl, cyano, COOR10 wherein R10 is hydrogen or C1 -C6 alkyl, and CONR11 R12 where R10 and R11 are independently selected from hydrogen and C1 -C6 alkyl, and the pharmaceutically acceptable salts thereof. The compounds are useful psychotherapeutics and may be used in treating obesity, depression and disorders wherein aggression is a symptom.