494799-16-5

Basic information

• Product Name: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid
• Synonyms: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid;3-cyclohexenyl-1H-indole-6-carboxylic acid;3-(1-cyclohexen-1-yl)-1H-Indole-6-carboxylic acid;3-(Cyclohex-1-enyl)-6-indolecarboxylic acid;3-(Cyclohex-1-enyl)-1H-indole-6-carboxylic acid
• CAS NO: 494799-16-5
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241
• Mol File: 494799-16-5.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 495.6±33.0 °C(Predicted)
• Appearance: /
• Density: 1.291±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.50±0.30(Predicted)
• CAS DataBase Reference: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid(494799-16-5)
• EPA Substance Registry System: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid(494799-16-5)

Safety Data

• Hazardous Substances Data: 494799-16-5(Hazardous Substances Data)

Usage

General Description

3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid is a chemical compound with a molecular formula C17H19NO2. It is a derivative of indole and contains a cyclohexene ring and a carboxylic acid group. 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid is commonly used in the pharmaceutical industry for the synthesis of various drugs and bioactive molecules. It exhibits a range of biological activities, including anti-inflammatory and antitumor properties. Additionally, it has been studied for its potential as a drug delivery system and as a building block in organic synthesis.

Upstream product

• 108-94-1 cyclohexanone 
• 50820-65-0 indole-6-carboxylic acid methyl ester 
• 1670-82-2 Indole-6-carboxylic acid 
• 202745-73-1 1-methyl-1H-indole-6-carboxylic acid 

Downstream Products

• 877270-31-0 5H-indolo[2,1-a][2]benzazepine-10-carboxylic acid, 13-cyclohexyl-6-(4-morpholinylcarbonyl)methyl ester 
• 1038924-00-3 7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid, 13-cyclohexyl-3-methoxy-, 10-(1,1-dimethylethyl) ester 
• 928844-30-8 13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid 10-(1,1-dimethylethyl) ester 6-methyl ester 
• 877271-71-1 methyl 13-cyclohexyl-6-(carboxy)-5H-indolo[2,1-a][2]-benzazepine-10-carboxylate 
• 936711-49-8 methyl 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylate 
• 844893-00-1 2-(4-benzyloxy-phenyl)-3-cyclohexyl-1-dimethylcarbamoylmethyl-1H-indole-6-carboxylic acid methyl ester 
• 735282-89-0 3-cyclohexyl-1-(2-morpholin-4-yl-2-oxoethyl)-2-phenyl-1H-indole-6-carboxylic acid 
• 774211-87-9 3-cyclohexyl-1-[2-(dimethylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-1H-indole-6-carboxylic acid 

Relevant articles and documents

HEPATITIS B CORE PROTEIN MODULATORS

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula:

MACROCYCLIC INDOLES AS HEPATITIS C VIRUS INHIBITORS

The present invention relates to inhibitors of HCV replication of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, formula (I), wherein R1; R3; and R4 have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.