494799-16-5

Basic information

• Product Name: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid
• Synonyms: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid;3-cyclohexenyl-1H-indole-6-carboxylic acid;3-(1-cyclohexen-1-yl)-1H-Indole-6-carboxylic acid;3-(Cyclohex-1-enyl)-6-indolecarboxylic acid;3-(Cyclohex-1-enyl)-1H-indole-6-carboxylic acid
• CAS NO: 494799-16-5
• Molecular Formula: C₁₅H₁₅NO₂
• Molecular Weight: 241
• Mol File: 494799-16-5.mol

Chemical Properties

• Boiling Point: 495.6±33.0 °C(Predicted)
• Appearance: /
• Density: 1.291±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.50±0.30(Predicted)
• CAS DataBase Reference: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid(494799-16-5)
• EPA Substance Registry System: 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid(494799-16-5)

Safety Data

• Hazardous Substances Data: 494799-16-5(Hazardous Substances Data)

Upstream product

• 50820-65-0 indole-6-carboxylic acid methyl ester 
• 108-94-1 cyclohexanone 
• 1670-82-2 Indole-6-carboxylic acid 
• 202745-73-1 1-methyl-1H-indole-6-carboxylic acid 

Downstream Products

• 494799-17-6 3-cyclohexyl-1-methyl-1H-indole-6-carboxylic acid 
• 494799-18-7 methyl 3-cyclohexyl-1H-indole-6-carboxylate 
• 494799-19-8 methyl 2-bromo-3-cyclohexyl-1H-indole-6-carboxylate 
• 494799-14-3 3-cyclohexyl-2-phenylindole-6-carboxylic acid methyl ester 
• 494799-15-4 3-cyclohexyl-2-phenyl-1H-indole-6-carboxylic acid 
• 494799-20-1 3-cyclohexyl-2-(3-furyl)indole-6-carboxylic acid methyl ester 
• 494799-21-2 3-cyclohexyl-1-methylindole-6-carboxylic acid methyl ester 
• 494799-22-3 2-bromo-3-cyclohexyl-1-methylindole-6-carboxylic acid methyl ester 
• 494799-77-8 3-cyclohexyl-2-furan-3-yl-1-methyl-1H-indole-6-carboxylic acid 
• 735287-38-4 [2-bromo-3-cyclohexyl-6-(methoxycarbonyl)-1H-indol-1-yl]acetic acid 
• 735287-01-1 methyl 2-bromo-3-cyclohexyl-1-[2-(dimethylamino)-2-oxoethyl]-1H-indole-6-carboxylate 
• 774213-79-5 methyl 2-bromo-1-(2-tert-butoxy-2-oxoethyl)-3-cyclohexyl-1H-indole-6-carboxylate 
• 774213-85-3 [3-cyclohexyl-6-(methoxycarbonyl)-2-phenyl-1H-indol-1-yl]acetic acid 
• 1027992-74-0 3-cyclohexyl-1-dimethylcarbamoylmethyl-2-phenyl-1H-indole-6-carboxylic acid methyl ester 

Relevant articles and documents

HEPATITIS B CORE PROTEIN MODULATORS

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula:

CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS

There is provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts or solvates thereof wherein one of R1 and R2 is H and the other is COOH. The compounds are useful as PPAR modulators.

MACROCYCLIC INDOLES AS HEPATITIS C VIRUS INHIBITORS

The present invention relates to inhibitors of HCV replication of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, formula (I), wherein R1; R3; and R4 have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Indolobenzazepine HCV NS5B inhibitors

The invention encompasses compounds and salts of Formulas I, II, III, and IV as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors

The invention encompasses compounds of Formula I, pharmaceutically acceptable salts thereof, compositions, and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS

Disclosed are compounds having formula I and related compositions and methods thereof. The compounds are useful for treating viral infections caused by the Flaviviridae family of viruses.