494803-93-9

Basic information

• Product Name: (S)-2-Acetylamino-4-methyl-pentanoic acid {(S)-1-[(E)-2-(1-benzenesulfonyl-1H-indol-3-yl)-vinylcarbamoyl]-2-phenyl-ethyl}-methyl-amide
• Synonyms: (S)-2-Acetylamino-4-methyl-pentanoic acid {(S)-1-[(E)-2-(1-benzenesulfonyl-1H-indol-3-yl)-vinylcarbamoyl]-2-phenyl-ethyl}-methyl-amide
• CAS NO: 494803-93-9
• Molecular Weight: 614.766
• Mol File: 494803-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-Acetylamino-4-methyl-pentanoic acid {(S)-1-[(E)-2-(1-benzenesulfonyl-1H-indol-3-yl)-vinylcarbamoyl]-2-phenyl-ethyl}-methyl-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Acetylamino-4-methyl-pentanoic acid {(S)-1-[(E)-2-(1-benzenesulfonyl-1H-indol-3-yl)-vinylcarbamoyl]-2-phenyl-ethyl}-methyl-amide(494803-93-9)
• EPA Substance Registry System: (S)-2-Acetylamino-4-methyl-pentanoic acid {(S)-1-[(E)-2-(1-benzenesulfonyl-1H-indol-3-yl)-vinylcarbamoyl]-2-phenyl-ethyl}-methyl-amide(494803-93-9)

Safety Data

• Hazardous Substances Data: 494803-93-9(Hazardous Substances Data)

Upstream product

• 1188-21-2 N-Ac-Leu 
• 494803-92-8 N-[2-(1-benzenesulfonyl-1H-indol-3-yl)-vinyl]-2-methylamino-3-phenyl-propionamide 
• 494803-88-2 {1-[2-(1-benzenesulfonyl-1H-indol-3-yl)-2-hydroxy-ethylcarbamoyl]-2-phenyl-ethyl}-methyl-carbamic acid tert-butyl ester 
• 494803-90-6 {1-[2-(1-benzenesulfonyl-1H-indol-3-yl)-vinylcarbamoyl]-2-phenyl-ethyl}-methyl-carbamic acid tert-butyl ester 
• 494803-91-7 N-[2-(1-benzenesulfonyl-1H-indol-3-yl)-2-hydroxy-ethyl]-2-methylamino-3-phenyl-propionamide 
• 494803-86-0 2-amino-1-(1-benzenesulfonyl-1H-indol-3-yl)-ethanol 
• 80360-20-9 1-(phenylsulfonyl)indole-3-carbaldehyde 
• 37553-65-4 Boc-N-Me-Phe-OH 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 

Relevant articles and documents

A short synthesis of aspergillamide B. The marine natural product from Aspergillus sp.

A short route to the marine natural product aspergillamide B has been developed. The key step is the stereoselective formation of the trans indole-enamide pharmacophore by indole-assisted dehydration from the functionalized aminoalcohol intermediate. HPLC and 1H NMR analyses show that aspergillamide B is more stable in the cis rotamer form.