4949-85-3

Basic information

• Product Name: 2,5-DICHLOROPHENYLTHIOUREA
• Synonyms: (2,5-dichlorophenyl)-thioure;1-(2,5-dichlorophenyl)-2-thio-ure;LABOTEST-BB LT00454457;2,5-DICHLOROPHENYLTHIOUREA;1-(2,5-DICHLOROPHENYL)-2-THIOUREA;1-(2,5-Dichlorophenyl)thiourea;Thiourea, N-(2,5-dichlorophenyl)-
• CAS NO: 4949-85-3
• Molecular Formula: C₇H₆Cl₂N₂S
• Molecular Weight: 221.11
• EINECS: -0
• Mol File: 4949-85-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 193-194°C
• Boiling Point: 317.4°Cat760mmHg
• Flash Point: 145.8°C
• Appearance: /
• Density: 1.563g/cm³
• Vapor Pressure: 0.000386mmHg at 25°C
• Refractive Index: 1.73
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2212146
• CAS DataBase Reference: 2,5-DICHLOROPHENYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DICHLOROPHENYLTHIOUREA(4949-85-3)
• EPA Substance Registry System: 2,5-DICHLOROPHENYLTHIOUREA(4949-85-3)

Safety Data

• Statements: 20/22-22
• Safety Statements: 22-36/37/39-36
• RIDADR: 2811
• RTECS: YS9275000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 4949-85-3(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C7H6Cl2N2S/c8-4-1-2-5(9)6(3-4)11-7(10)12/h1-3H,(H3,10,11,12)

Upstream product

• 333-20-0 potassium thioacyanate 
• 33663-41-1 2,5-dichloroaniline hydrochloride 
• 3386-42-3 (2,5-dichlorophenyl)isothiocyanate 
• 95-82-9 2,5 dichloroaniline 
• 1147550-11-5 ammonium thiocyanate 
• 6281-57-8 N-(2,5-dichlorophenyl)-N'-benzoylthiocarbamide 

Downstream Products

• 103753-74-8 2-(2,5-dichloro-anilino)-5-methyl-thiazol-4-one 
• 30895-24-0 1-(2,5-dichlorophenyl)-5-amino-1H-tetrazole 
• 929562-45-8 C₁₈H₁₅Cl₂N₃O₂S 
• 929562-40-3 C₁₆H₁₂Cl₂N₂OS 
• 929561-59-1 C₁₇H₁₄Cl₂N₂OS 
• 929562-02-7 C₁₂H₁₀Cl₂N₂OS 
• 132841-34-0 N-(2,5-Dichloro-phenyl)-N-[4-(3,3,7,8-tetramethyl-1-oxo-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-11-yl)-thiazol-2-yl]-acetamide 
• 132841-32-8 N-(2,5-Dichloro-phenyl)-N-[4-(3,3-dimethyl-1-oxo-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-11-yl)-thiazol-2-yl]-acetamide 
• 132841-29-3 4-formyl-2-(N-acetyl-N-phenyl-2,5-dichlorophenyl)thiazole 
• 69347-87-1 1-(2,5-dichlorophenyl)-2-methylisothiouronium iodide 
• 132841-37-3 4-chloromethyl-2-(N-acetyl-N-2,5-dichlorophenyl)thiazole 
• 852-06-2 2-[2-(2,5-dichloro-anilino)-5-methyl-thiazol-4-yl]-4-fluoro-phenol 
• 2648-22-8 2-[2-(2,5-dichloro-anilino)-thiazol-4-yl]-4-fluoro-phenol 
• 107329-06-6 17β-[2-(2,5-dichloro-anilino)-thiazol-4-yl]-17α-hydroxy-androst-4-en-3-one 

Relevant articles and documents

Eco-efficient one-pot tandem synthesis of 1-aryl-1H-tetrazol-5-amine by CAN via in situ generated 1-phenylthiourea and heterocumulene

A simple, cost-effective, environmentally benign, and efficient one-pot tandem approach to the synthesis of pharmaceutically important 1-aryl-1H-tetrazole-5-amines 3a-k and 4a-k has been described. The reaction utilized 1-phenyl thiourea, which was generated in situ from aqueous ammonia and isocyanates 1a-k, for the formation of heterocumenes using sodium azide, triethylamine, and ceric ammonium nitrate (CAN) to obtain various aryl-substituted 1H-tetrazole-5-amines (3a-k) in good to excellent yields.

Chemical screening of novel strigolactone agonists that specifically interact with DWARF14 protein

Strigolactones (SLs) are a class of plant hormones that regulate shoot branching as well as being known as root-derived signals for parasitic and symbiotic interactions. The physical interaction between SLs and the DWARF14 (D14) receptor family can be examined by differential scanning fluorimetry (DSF) that monitors the changes in protein melting temperature (Tm). The Tm of D14 is lowered by bioactive SLs in DSF analysis. In this report, we screened the compounds that lower the Tm of Arabidopsis D14 (AtD14) as potential candidates for SL agonists using DSF analysis. Subsequent physiological analyzes revealed that 113D10 acts as a novel SL agonist in a D14-dependent manner. Intriguingly, 113D10 has a chemical structure different from natural SLs in that it does not possess an enol ether bond that connects to a methylbutenolide moiety. Moreover, 113D10 does not stimulate seed germination of root parasitic plants. Accordingly, 113D10 can be a useful tool for SL studies and agricultural applications.