495-27-2

Usage

Uses

Used in Food and Beverage Industry:
OPHTHALMIC ACID is used as an additive for enhancing the cooling sensation in the food and beverage industry. It contributes to the overall sensory experience of consumers by providing a refreshing and cooling effect when incorporated into products.
Used in Flavor Composition:
In the flavor composition industry, OPHTHALMIC ACID is utilized as a key component in creating and modifying the taste profiles of various products. Its unique properties allow it to enhance and complement the flavors of different food and beverage items, resulting in a more enjoyable and distinct taste experience for consumers.

InChI:InChI=1/C11H19N3O6/c1-2-7(10(18)13-5-9(16)17)14-8(15)4-3-6(12)11(19)20/h6-7H,2-5,12H2,1H3,(H,13,18)(H,14,15)(H,16,17)(H,19,20)/t6-,7-/m0/s1

Upstream product

• 103506-39-4 N-{(S)-2-[(N-benzyloxycarbonyl-L-γ-glutamyl)-amino]-butyryl}-glycine 
• 3705-42-8 Cbz-(L)-Glu-OBn 
• 16305-80-9 L-α-Amino-butyryl-glycin 
• 92235-10-4 N-((S)-2-benzyloxycarbonylamino-butyryl)-glycine ethyl ester 
• 2747-97-9 N--glycin-<4-nitro-benzylester> 
• 13030-09-6 1-benzyl L-glutamate 
• 801143-15-7 N--glycin-<4-nitro-benzylester> 
• 2747-99-1 N-(4-Nitro-benzyloxycarbonyl)-L-glutaminsaeure-1-benzylester 
• 16305-77-4 N-Benzyloxycarbonyl-L-α-amino-butyryl-glycin-benzylester 

Relevant academic research and scientific papers

A turn-on NIR fluorescence and colourimetric cyanine probe for monitoring the thiol content in serum and the glutathione reductase assisted glutathione redox process

We report a novel reaction-based thiol selective turn-on near-infrared (NIR) fluorescence and colourimetric dinitrobenzenesulfonyl-cyanine (DNBSCy) probe. In the presence of thiols such as glutathione (GSH), new absorption bands (476 and 581 nm) were observed, with the colour of the solution (10 mM PBS, pH = 7.4) changing from light green to blue. Interestingly, relatively non-fluorescent DNBSCy exhibited enhanced fluorescence emission around 700 nm in the NIR region. GSH reacted efficiently with the electron withdrawing sulfonyl ester moiety of DNBSCy, releasing the quinone embedded heptamethine cyanine (Cy-quinone) with extended π-electron conjugation responsible for the turn-on NIR fluorescence. Cy-quinone also displayed a conjugated π-electron push-pull character under physiological conditions. The DNBSCy probe was effectively employed to monitor the thiols in fetal bovine serum (FBS). The probe was capable of monitoring the oxidized glutathione (GSSG)/GSH redox process in the presence of glutathione reductase and NADPH with NIR fluorescence and colourimetric optical response. Thus, DNBSCy has the potential to measure the activity of glutathione reductase as a measure of oxidative stress. The Royal Society of Chemistry 2013.

COMPARISON OF CONFORMATIONS OF OPHTHALMIC AND TOPOOPHTHALMIC ACIDS IN AQUEOUS SOLUTIONS

A new synthesis of ophthalmic acid is described.The comparison of CD and 1H NMR spectra of ophthalmic and topoophthalmic acids in water enables us to conclude that both these peptides differ distinctly in their mean solution conformations.