49559-34-4

Basic information

• Product Name: BENZOXAZOLE, 2-CHLORO-5-METHOXY-
• Synonyms: BENZOXAZOLE, 2-CHLORO-5-METHOXY-;2-chloro-5-methoxybenzo[d]oxazole;2-chloro-5-methoxyBenzoxazole;2-Chloro-5-methoxy-1,3-benzoxazole
• CAS NO: 49559-34-4
• Molecular Formula: C₈H₆ClNO₂
• Molecular Weight: 183.6
• EINECS: 604-604-1
• Mol File: 49559-34-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 251°C at 760 mmHg
• Flash Point: 105.6°C
• Appearance: /
• Density: 1.354g/cm³
• Vapor Pressure: 0.0332mmHg at 25°C
• Refractive Index: 1.595
• PKA: 2.99±0.10(Predicted)
• CAS DataBase Reference: BENZOXAZOLE, 2-CHLORO-5-METHOXY-(CAS DataBase Reference)
• NIST Chemistry Reference: BENZOXAZOLE, 2-CHLORO-5-METHOXY-(49559-34-4)
• EPA Substance Registry System: BENZOXAZOLE, 2-CHLORO-5-METHOXY-(49559-34-4)

Safety Data

• Hazardous Substances Data: 49559-34-4(Hazardous Substances Data)

Usage

General Description

Benzoxazole, 2-chloro-5-methoxy- is a chemical compound with the molecular formula C8H6ClNO2. It is a heterocyclic compound that contains a benzene ring fused to an oxazole ring. BENZOXAZOLE, 2-CHLORO-5-METHOXY- is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its diverse biological activities. It has been found to possess antifungal, antibacterial, and anticancer properties, making it a valuable intermediate in the development of new drugs. However, it is important to handle this chemical with care as it can be hazardous if not used properly, and proper safety precautions should be taken when working with it.

InChI:InChI=1/C8H6ClNO2/c1-11-5-2-3-7-6(4-5)10-8(9)12-7/h2-4H,1H3

Upstream product

• 49559-83-3 2-mercapto-5-metossi-benzossazolo 
• 1568-70-3 4-methoxy-2-nitrophenol 
• 67-72-1 hexachloroethane 
• 20734-76-3 2-amino-4-methoxyphenol 
• 49559-83-3 5-methoxybenzo[d]oxazole-2(3H)-thione 

Downstream Products

• 1312543-46-6 N-(3-tert-butylphenyl)-5-methoxybenzo[d]oxazol-2-amine 
• 1312543-51-3 2-(3-tert-butylphenylamino)benzo[d]oxazol-5-ol hydrobromide 
• 1312543-43-3 4-(2-(3-tert-butyl phenylamino)benzo[d]oxazol-5-yloxy)-N-methylpicolinamide 
• 611225-73-1 (4-bromo-phenyl)-(5-methoxy-benzoxazol-2-yl)-amine 

Relevant articles and documents

SUBSTITUENT-INCLUDING UREA COMPOUND

An object of the present invention is to provide a compound that has a specific chemical structure having an activation effect on SIRT6 and is useful as an active component for preventing and treating inflammatory diseases. The present invention relates to a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. (Each symbol in Formula (1) has the same definition as that described in the specification.)

OCTAHYDROPYRROLO [3, 4-c] PYRROLE DERIVATIVES AND USES THEREOF

The invention relates to octahydropyrrolo [3, 4-c] pyrrole derivatives and uses thereof. Compounds and pharmaceutical compositions comprising the compounds provided herein are used for antagonizing orexin receptors. The invention also relates to processes for preparing the compounds and pharmaceutical compositions, and uses thereof in treating or preventing a disease related to orexin receptors.

Analgesic Compounds, Compositions, and Uses Thereof

The invention relates to compounds, compositions, and methods for diminishing pain in a subject in need thereof comprising administering the compounds and compositions herein described.