49559-65-1 Usage
Uses
Used in Pharmaceutical Industry:
5-Chloro-benzooxazole-2-carboxylic acid is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs targeting specific diseases.
Used in the Treatment of β-Amyloid-Related Diseases:
5-Chloro-benzooxazole-2-carboxylic acid is used as a therapeutic agent for preventing, treating, or reducing the impact of β-amyloid-related diseases, such as Alzheimer's disease. 5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID may help in modulating the aggregation and deposition of β-amyloid peptides, which are known to contribute to the pathology of these diseases.
Used in Chemical Research:
5-Chloro-benzooxazole-2-carboxylic acid can be utilized as a research tool in the field of organic chemistry, particularly in the study of benzooxazole derivatives and their potential applications in various chemical and biological processes.
Used in Material Science:
5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID may also find applications in the development of new materials, such as polymers and coatings, due to its unique chemical properties and the ability to form stable complexes with other molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 49559-65-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,9,5,5 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 49559-65:
(7*4)+(6*9)+(5*5)+(4*5)+(3*9)+(2*6)+(1*5)=171
171 % 10 = 1
So 49559-65-1 is a valid CAS Registry Number.
InChI:InChI=1S/C8H4ClNO3/c9-4-1-2-6-5(3-4)10-7(13-6)8(11)12/h1-3H,(H,11,12)
49559-65-1Relevant academic research and scientific papers
Direct C-H carboxylation with carbon dioxide using 1,2,3-triazol-5-ylidene copper(I) complexes
Inomata, Hiroshi,Ogata, Kenichi,Fukuzawa, Shin-Ichi,Hou, Zhaomin
supporting information; experimental part, p. 3986 - 3989 (2012/09/10)
1,2,3-Triazol-5-ylidene copper(I) complexes (tzNHC-Cu) efficiently catalyzed the direct C-H carboxylation of benzoxazole and benzothiazole derivatives with CO2 to give the corresponding esters in excellent yields after treatment with alkyl iodi
Carbon dioxide as the C1 source for direct C-H functionalization of aromatic heterocycles
Vechorkin, Oleg,Hirt, Nathalie,Hu, Xile
supporting information; experimental part, p. 3567 - 3569 (2010/10/02)
(Equation Presented). A simple and straightforward method has been developed for the direct carboxylation of aromatic heterocylces such as oxazoles, thiazoles, and oxadiazoles using CO2 as the C1 source. The reactions require no metal catalyst and only Cs2CO3 as the base. A good functional group tolerance is achieved.
