27383-92-2

Basic information

• Product Name: 5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER
• Synonyms: 5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER;methyl 5-chlorobenzo[d]oxazole-2-carboxylate;2-Benzoxazolecarboxylic acid, 5-chloro-, Methyl ester;5-Chloro-2-benzoxazolecarboxylic acid methyl ester;Methyl 5-chloro-2-benzoxazolecarboxylate;5-chloro-benzoxazole-2-carboxylic acid methyl ester
• CAS NO: 27383-92-2
• Molecular Formula: C9H6ClNO3
• Molecular Weight: 211.61
• EINECS: 200-589-5
• Mol File: 27383-92-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: 124 °C
• Boiling Point: 309.1°C at 760 mmHg
• Flash Point: 140.7°C
• Appearance: /
• Density: 1.416
• Vapor Pressure: 0.000653mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -1.88±0.10(Predicted)
• CAS DataBase Reference: 5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER(27383-92-2)
• EPA Substance Registry System: 5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER(27383-92-2)

Safety Data

• Hazardous Substances Data: 27383-92-2(Hazardous Substances Data)

Usage

General Description

5-CHLORO-BENZOOXAZOLE-2-CARBOXYLIC ACID METHYL ESTER is a chemical compound with the molecular formula C9H6ClNO3. It is a methyl ester derivative of 5-chloro-benzooxazole-2-carboxylic acid, which is a heterocyclic organic compound. This chemical is commonly used in the pharmaceutical industry as a building block for the synthesis of various drug molecules and pharmaceutical intermediates. It has also shown potential biological activity and is used as a reference standard in chemical and biological research. Additionally, it is used in the production of agrochemicals, dyes, and other specialty chemicals.

InChI:InChI=1/C9H6ClNO3/c1-13-9(12)8-11-6-4-5(10)2-3-7(6)14-8/h2-4H,1H3

Upstream product

• 33652-89-0 5-chlorobenzo[d]oxazole-2-carbonitrile 
• 74-88-4 methyl iodide 
• 17200-29-2 5-chloro-benzoxazole 
• 49559-65-1 5-chloro-benzooxazole-2-carboxylic acid 
• 124-38-9 carbon dioxide 
• 3621-81-6 2,5-dichloro-1,3-benzoxazole 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 58772-56-8 6-chloro-4-hydroxy-2,3-dimethoxycarbonyl-1,4-benzoxazine 
• 18370-95-1 methyl 2,2,2-trimethoxyacetate 
• 95-85-2 2-hydroxy-5-chloro-aniline 
• 33681-67-3 5-chloro-benzooxazole-2-carboximidic acid methyl ester 

Relevant articles and documents

Studies on Copper(II) Complexes of ortho-Quinone Mono-oximes: Reaction of Bis(4-chloro-1,2-benzoquinone 2-oximato)copper(II) with Dimethyl Acetylenedicarboxylate under Various Experimental Conditions

In anhydrous methanol the title complex reacts with dimethyl acetylenedicarboxylate to give methyl 5-chloro-1,3-benzoxazole-2-carboxylate instead of 6-chloro-4-hydroxy-2,3-dimethoxycarbonyl-1,4-benzoxazine as in aqueous solution.The role of water in such

Binuclear molybdenum alkoxide as the versatile catalyst for the conversion of carbon dioxide

The triply bonded dimolybdenum compound, Mo2(OtBu)6 (1), was investigated as a homogeneous catalyst for the conversion of CO2. The compound 1 acted as a rare example of a versatile catalyst with an impressive ability to transform CO2 into various valuable products, including propiolic acids, cyclic carbonates, and benzo[d]thiazole- and benzo[d]oxazolecarboxylic acids, in high yields with short reaction times and excellent selectivity at ambient pressure and low temperatures (25-75 °C). This is the first report of the application of a metal-metal bond-containing species in the catalytic conversion of CO2.

C-H carboxylation of heteroarenes with ambient CO2

The C-H carboxylation of heteroarenes was achieved under transition metal-free reaction conditions with naturally abundant CO2 as the C1 source at relatively low temperature. The C-H carboxylation was mediated by KOt-Bu at atmospheric pressure