49571-48-4Relevant academic research and scientific papers
Synthesis of novel β-aryl-β-(methylthio)acroleins via Vilsmeier-Haack protocol as potential 1,3-dielectrophilic three-carbon building blocks
Byre Gowda,Charanraj,Pradeepa Kumara,Ramesh,Thomas,Sadashiva,Junjappa
, p. 4475 - 4479 (2014/08/05)
A new general route for the synthesis of novel β-aryl-β- (methylthio)acroleins, a class of stable potential 1,3-dielectrophilic synthons, has been reported. The overall protocol involves treatment of either β-chloroacroleins or their precursor iminium salts (generated in situ from the corresponding active methylene ketones under Vilsmeier-Haack reaction conditions) with S,S-dimethyldithiocarbonates (DDC)/aqueous KOH in either a one-pot or two-step process. The dimethyldithiocarbonate (DDC)/30% aqueous KOH has been shown to be an excellent source of methylthiolate anion.
ENAMINE CHEMISTRY-XIX PREPARATION AND ALKYLATION OF CYCLIC AND NON-CYCLIC ENAMINO-THIONES
Rasmussen, J. B.,Shabana, R.,Lawesson, S.-O.
, p. 197 - 202 (2007/10/02)
Enamino-thiones of the general type ArC(S)CH:CHNR2, 3 (Ar = phenyl, p-methoxyphenyl and p-bromophenyl, NR2 = pyrrolidinyl, piperidino), were prepared by reacting the corresponding enaminones, 2, with 2,4-bis-(4-methoxyphenyl)-1,3,2,4
