41125-10-4

Upstream product

• 98-86-2 acetophenone 
• 109-94-4 formic acid ethyl ester 
• 107-31-3 Methyl formate 

Downstream Products

• 53704-24-8 4-(1-ethyl-1H-quinolin-2-ylidene)-1-phenyl-but-2-en-1-one 
• 43083-13-2 3-cyano-2-hydroxy-6-phenylpyridine 
• 15724-86-4 E-2-chlorovinyl phenyl ketone 
• 3438-48-0 4-phenylpyrimidine 
• 25871-69-6 1,3,5-tribenzoylbenzene 
• 55735-49-4 3-acetoxy-1-phenyl-propenone 
• 3754-17-4 N-<3-Hydroxy-3-phenyl-propenyliden>-2-aethylsulfamoyl-5-chlor-4-sulfamoyl-anilin 
• 3949-83-5 N-<3-Hydroxy-3-phenyl-propenyliden>-2-allylsulfamoyl-5-chlor-4-sulfamoyl-anilin 
• 35327-87-8 4-(3-ethyl-3H-benzothiazol-2-ylidene)-1-phenyl-but-2-en-1-one 
• 94298-88-1 ω-m-Anisidino-acrylophenon 
• 60848-27-3 6-hydroxy-9-phenyl-1H-phenalen-1-one 
• 87618-29-9 4-benzoyl-2-phenyl-6H-phenaleno<1,9-bc>pyran-6-one 
• 118947-88-9 6-Phenyl-2-selenoxo-1,2-dihydro-pyridine-3-carbonitrile 
• 99482-91-4 4-phenyl-3-cyano-2(1H)-pyridineselenone 

Relevant academic research and scientific papers

A Method for the Preparation of β-Amino-α,β-unsaturated Carbonyl Compounds: Study of Solvent Effect and Mechanism

An efficient method for the preparation of β-amino-α,β-unsaturated carbonyl compounds is demonstrated. Bench-stable sodium 3-oxo-enolates were prepared from carbonyl compounds, and reacted with amines in the presence of an acid and a desiccant. DFT studie

Thiophosphoryl-Functionalized enaminoketones: Synthesis, structure, and complexing properties towards transition metal ions

P(X)-functionalized enaminoketones (X = O, S) 1a,b have been readily obtained by the condensation of o-(thio)phosphorylated anilines with sodium salt of benzoylacetaldehyde. The ligands derived exist in solution in the expected ketamino tautomeric form, b

Synthesis and antibacterial evaluation of novel 4-alkyl substituted phenyl β-aldehyde ketone derivatives

A series of novel 4-alkylphenyl β-aldehyde ketones and their derivatives were designed and synthesized on the basis of the chemical structures of Houttuynin and β-lactam antibiotics. Antibacterial activities of these compounds were investigated. The results demonstrated that most of the compounds tested had moderate antibacterial activities against Gram-positive pathogen Staphylococcus aureus (ATTC-25923) than Houttuynin, and Gram-positive bacteria were more susceptible to the compounds than Gram-negative bacteria. Compound 23 was found to be the most potent compound with MIC of 1.0 μg/mL against S. aureus. Particularly, compounds 16, 22 and 23 showed more active antibacterial activities against the clinically important pathogenic bacteria, methicillin-resistant S. aureus (MRSA) than Houttuynin and levofloxacin. The preliminary structure-activity relationship (SAR) analysis suggested that (1) the introduction of appropriate alkyl substituents into position 4 of phenyl ring enhanced antibacterial activities of these compounds, and isopropyl substituent might be more favorable; (2) the presence of ketone carbonyl moiety might play a vital role in determining significant antibacterial activities of these compounds.

PROCESS FOR PRODUCING 3-SUBSTITUTED THIOPHENE

A process for producing a 3-substituted thiophene represented by the general formula (2): (wherein R represents cyano, formyl, carboxy, optionally substituted hydrocarbyloxycarbonyl, or optionally substituted acyl), characterized by reacting a vinyl compound represented by the general formula (1): RCH=CHY (wherein R has the same meaning as defined above; and Y is a leaving group) with α-mercaptoacetaldehyde or a polymer thereof.