10406-24-3Relevant articles and documents
An efficient hydrogenation of dinitrile to aminonitrile in supercritical carbon dioxide
Chatterjee, Maya,Sato, Masahiro,Kawanami, Hajime,Yokoyama, Toshirou,Suzuki, Toshishige,Ishizaka, Takayuki
, p. 2394 - 2398 (2010)
The highly selective hydrogenation of adiponitrile proceeds effectively in supercritical carbon dioxide (scCO2) to produce 6-aminocapronitrile with excellent selectivity of 100% over rhodium/alumina (Rh/Al2O 3) and without any additive, which is impossible in classical organic solvents. The presence of CO2 can be beneficial or mandatory for the exclusive formation of the aminonitrile as it can act as a solvent to enhance the activity and also as temporary protecting agent to increase the selectivity. These results successfully show the general concept of using scCO2 as a protective medium for the selectivity control of dinitrile to aminonitrile reactions. Recycling of the catalyst and further extension of this method to other dinitriles were also investigated.
2-IMIDAZOLYL-PYRIMIDINE SCAFFOLDS AS POTENT AND SELECTIVE INHIBITORS OF NEURONAL NITRIC OXIDE SYNTHASE
-
, (2016/01/25)
Imidazolyl-pyrimidine and related compounds, as can utilize heme-iron coordination in the selective inhibition of neuronal nitric oxide synthase.
One-pot primary aminomethylation of aryl and heteroaryl halides with sodium phthalimidomethyltrifluoroborate
Murai, Norio,Miyano, Masayuki,Yonaga, Masahiro,Tanaka, Keigo
supporting information; experimental part, p. 2818 - 2821 (2012/07/17)
A one-pot primary aminomethylation of aryl halides, triflates, mesylates, and tosylates via Suzuki-Miyaura cross-coupling reactions with sodium phthalimidomethyltrifluoroborate followed by deamidation with ethylenediamine is reported.