49660-92-6

Upstream product

• 2403-55-6 4-(2-methyl-1-propenyl)morpholine 
• 121-90-4 m-nitrobenzoic acid chloride 
• 611-70-1 phenyl isopropyl ketone 

Downstream Products

• 280760-05-6 C₁₀H₁₃N₃O₂ 
• 1366133-36-9 C₂₁H₃₄N₂O₂S 
• 5912-95-8 α-(1-methylethyl)-3-nitrobenzenemethanol 
• 36025-19-1 2-bromo-2-methyl-1-(3-nitrophenyl)propan-1-one 
• 42528-67-6 m-amino isobutyrophenone 
• 218300-43-7 [3-(1-amino-2-methyl-propyl)-phenyl]-urea 
• 218300-32-4 (3-isobutyryl-phenyl)-urea 

Relevant academic research and scientific papers

Process for synthesizing m-isobutylaniline

The invention relates to a process for synthesizing m-isobutylaniline. According to the invention, isobutyraldehyde and morpholine are used as starting materials and p-toluenesulfonic acid is used as a catalyst to synthesize 2-methyl-1-m-morpholinylpropylene; then 2-methyl-1-m-morpholinylpropylene and nitrobenzoyl chloride are subjected to condensation and hydrolysis, and then an aldehyde group is removed under the action of hydrochloric acid, so m-nitrophenylisobutyl ketone is synthesized; then m-aminophenylisobutyl ketone is synthesized through selective hydrogenation; and finally, m-isobutylaniline is synthesized through a Huang Minglong reaction.

NEW CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS

The invention relates to compounds of the general formula (I): to the process for preparing them, and to the use thereof as a therapeutic agent.

3-Azabicyclo[3.1.0]hexane derivatives useful in therapy

Compounds of formula (I), their salts and prodrugs thereof, where the substituents are as defined herein are disclosed as opiate binding agents useful in the treatment of opiate-mediated conditions. Also described are processes for making such substances.

Ozone-mediated Nitration of Aromatic Ketones and Related Compounds with Nitrogen Dioxide

Alkyl aryl ketones react smoothly with nitrogen dioxide at low temperatures in the presence of ozone to give ortho- and meta-nitro derivatives as the principal products, the former usually being predominant (ortho:meta = 1.1-3.8:1.0).No attack was observed on the alkyl side chains.

1,5-Diphenyl-1H-1,2,4-triazole-3-carboxamide derivatives, process for preparation of the same, antifungal composition comprising the same

A derivative of 1,5-diphenyl-1H-1,2,4-triazole-3-carboxamide represented by the following general formula (I), a process for the manufacture thereof, and an antimicrobial composition comprising it as an effective component wherein R1 is a C1-C

1-Phenyl-5-heterocyclic-1H-1, 2,4-triazole-3-carboxamide derivates, process for preparation of the same, and fungicidal composition comprising the same

A derivative of 1-phenyl-5-heterocyclic-1H-1,2,4-triazole-3-carboxamide represented by the following general formula (I), a process for the manufacture thereof, and an fungicidal composition comprising the same as an active ingredient. wherein R1 is a Cs

1-phenyl-5-substituted-1H-1, 2,4-triazole-3-carboxamide derivates, process for preparation of the same, and fungicidal composition comprising the same

A derivative of 1-phenyl-5-substituted-1H-1,2,4-triazole-3-carboxamide represented by the following general formula (I), a process for the manufacture thereof, and an fungicidal composition comprising the same as an active ingredient. wherein R1 is a Csu