497063-19-1Relevant academic research and scientific papers
Synthesis of 3-oxo oxacycloalkenes by ring closing metathesis
Cossy, Janine,Taillier, Catherine,Bellosta, Véronique
, p. 7263 - 7266 (2002)
The synthesis of six-, seven- and eight-membered 3-oxo oxacycloalkenes by using ring-closing metathesis has been achieved from 1-(ω-alkenyloxy)-but-3-en-2-ones.
Synthesis of 3-oxooxa- and 3-oxoazacycloalk-4-enes by ring-closing metathesis. Application to the synthesis of an inhibitor of cathepsin K
Taillier, Catherine,Hameury, Thomas,Bellosta, Véronique,Cossy, Janine
, p. 4472 - 4490 (2008/02/01)
3-Oxooxa- and 3-oxoazacycloalk-4-enes were obtained with good yield from 1-(ω-alkenyloxy)- and 1-(ω-alkenylamino)-but-3-en-2-ones by using a ring-closing metathesis. This methodology has been used to synthesize an inhibitor of cathepsin K.
