497107-22-9

Upstream product

• 327039-85-0 (5S,13S)-21-methoxy-5,13-diphenyl-3,6,9,12,15-pentaoxabicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-triene 
• 118249-11-9 5-bromo-1,3-bis(bromomethyl)-2-methoxybenzene 
• 94199-20-9 (S)-(+)-2-phenyl-2-(tetrahydropyranyloxy)ethanol 
• 497107-20-7 5-bromo-1,3-bis[(4S)-4-hydroxy-4-phenyl-2-oxobutyl]-2-methoxybenzene 
• 497107-21-8 (5S,13S)-19-bromo-21-methoxy-5,13-diphenyl-3,6,9,12,15-pentaoxabicyclo[15.3.1]henicosa-1⁽²⁰⁾,17⁽²¹⁾,18-triene 
• 666837-01-0 C₃₅H₄₃BrO₇ 

Relevant academic research and scientific papers

Preparation of phenolic chiral crown ethers and podands and their enantiomer recognition ability toward secondary amines

Phenolic pseudo-24-crown-8 (S,S)-3, pseudo-27-crown-9 (S,S)-4, and podands (R,R)-5 and (R,R)-6 possessing phenyl groups as chiral barriers were prepared and their chiral recognition properties toward secondary neutral amines were examined. Pseudo-24-crown-8 (S,S)-3 and podand (R,R)-5 showed sufficient binding ability and moderate chiral recognition ability toward secondary amines.

Chiral recognition of secondary amines by using chiral crown ether and podand

Chiral crown ether (S,S)-3 having a pseudo-24-crown-8 ring and chiral podand (R,R)-4 were prepared and both exhibited good chiral recognition ability toward secondary amines, N-α-dimethylbenzylamine (15) and propranolol (16).