497147-92-9Relevant academic research and scientific papers
2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors
Mackman, Richard L.,Hui, Hon C.,Breitenbucher,Katz, Bradley A.,Luong, Christine,Martelli, Arnold,McGee, Danny,Radika, Kesavan,Sendzik, Martin,Spencer, Jeffrey R.,Sprengeler, Paul A.,Tario, James,Verner, Erik,Wang, Jing
, p. 2019 - 2022 (2002)
The development of potent and selective urokinase-type plasminogen activator (uPA) inhibitors based on the lead molecule 2-(2-hydroxy-3-ethoxyphenyl)-1H-benzimidazole-5-carboxamidine (3a) is described.
