497155-65-4Relevant academic research and scientific papers
ZnCl2-mediated stereoselective addition of terminal alkynes to D-(+)-mannofuranosyl nitrones
Topic, Dana,Aschwanden, Patrick,Faessler, Roger,Carreira, Erick M.
, p. 5329 - 5330 (2007/10/03)
(Chemical Equation Presented) An optimized process for the addition of terminal alkynes to chiral nitrones using ZnCl2 and NEt3 in toluene is reported. The new reaction protocol is facile to perform and cost-effective. The resulting
1,2,4-Oxadiazolidinones as configurationally stable chiral building blocks
Ritter, Tobias,Carreira, Erick M.
, p. 936 - 938 (2007/10/03)
An intriguing scaffold for drug development, 1,2,4-oxadiazolidinones are obtained in enantiomerically pure form by a simple reaction and purification protocol (see scheme). These heterocycles, including the previously unknown N2-unsubstituted parent struc
