497181-14-3

Upstream product

• 726-26-1 phenyl 3-phenylpropanoate 
• 106-53-6 para-bromobenzenethiol 
• 23522-73-8 3-phenylpropionic acid 4-chlorophenyl ester 
• 501-52-0 3-Phenylpropionic acid 
• 497180-96-8 S-(4-trimethylsilylphenyl)-N,N-dimethylaminothiocarbamate 
• 497180-93-5 O-(4-trimethylsilylphenyl)-N,N-dimethylaminothiocarbamate 
• 497181-12-1 1-phenyl-3-(4-trimethylsilylphenyl)thiopropane 
• 18036-81-2 trimethyl-(4-trimethylsilanyloxy-phenyl)-silane 
• 17882-12-1 4-trimethylsilylbenzenethiol 
• 13132-25-7 4-(trimethylsilyl)phenol 
• 106-41-2 4-bromo-phenol 

Downstream Products

• 1330062-55-9 (R)-4-bromophenyl 3-phenylpropyl sulfoxide 
• 742086-05-1 1-bromo-4-((3-phenylpropyl)sulfonyl)benzene 

Relevant academic research and scientific papers

Indium-Catalyzed Reductive Sulfidation of Esters by Using Thiols: An Approach to the Diverse Synthesis of Sulfides

A new reductive preparation of unsymmetrical sulfides from esters and thiols in the presence of InI3 and either 1,1,3,3-tetramethyldisiloxane (TMDS) or PhSiH3 as the reductant was developed. This protocol was applied to not only benzoic acid esters that have a methoxy, methyl, chloro, bromo, iodo, or trifluoromethyl group on the aromatic ring but also aliphatic acid esters with either aromatic or aliphatic thiols. A reaction mechanism is proposed by using Hammett plot results and several control experiments. The reductive preparation of unsymmetrical sulfides from esters and thiols by using InI3 and either 1,1,3,3-tetramethyldisiloxane (TMDS) or PhSiH3 was developed. Several mechanistic studies support that the present transformation proceeds through O,S-and S,S-acetals as the reaction intermediates. TMDS = 1,1,3,3-tetramethyldisiloxane, R = aliphatic group.

Synthetic equivalents of benzenethiol and benzyl mercaptan having faint smell: Odor reducing effect of trialkylsilyl group

Syntheses and odor tests of the trialkylsilylated benzyl mercaptans and benzenethiols have revealed that the trimethylsilyl substituent on the benzene ring has a remarkable effect in reducing the foul smell of the parent benzyl mercaptan and benzenethiol.