49754-15-6

Usage

Uses

Used in Pharmaceutical Synthesis:
Diethyl malonyldicarbamate is used as a reagent for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its ability to form stable complexes with metal ions and its high reactivity and selectivity facilitate efficient and precise chemical transformations in the production of complex organic molecules.
Used in Agrochemical Production:
In the agrochemical industry, Diethyl malonyldicarbamate is utilized as a reagent for the synthesis of agrochemicals, aiding in the development of pesticides and other agricultural chemicals that are essential for crop protection and yield enhancement.
Used in Dye Synthesis:
DEMDC is employed as a building block in the synthesis of dyes, where its unique properties contribute to the creation of a wide range of colorants used in various industries, including textiles, plastics, and printing.
Used in Metal-Catalyzed Reactions:
Diethyl malonyldicarbamate is used as a complexing agent in metal-catalyzed reactions, taking advantage of its ability to form stable complexes with metal ions to improve the efficiency and selectivity of these reactions.
Used in Medicinal Chemistry Research:
DEMDC is used as a research tool in medicinal chemistry, where its properties are leveraged to explore new chemical pathways and develop innovative drug candidates.

InChI:InChI=1/C9H14N2O6/c1-3-16-8(14)10-6(12)5-7(13)11-9(15)17-4-2/h3-5H2,1-2H3,(H,10,12,14)(H,11,13,15)

Upstream product

• 141-82-2 malonic acid 
• 51-79-6 urethane 
• 1663-67-8 malonoyl dichloride 
• 861535-09-3 N,N'-bis-ethoxycarbonyl-2-bromo-malonic acid diamide 
• 64-19-7 acetic acid 

Downstream Products

• 39772-80-0 N,N'-(phenylhydrazono-malonyl)-bis-carbamic acid diethyl ester 
• 49754-25-8 (3,5-dioxo-2-phenyl-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carbonyl)-carbamic acid ethyl ester 
• 621-10-3 N,N'-diphenylmalonamide 
• 603-54-3 N,N-diphenylurea 
• 69360-81-2 3,5-dichloro-4-methylthio-phenylhydrazonomalonyl diurethane 
• 69360-73-2 (2-{[3,5-Dichloro-4-(3-methyl-4-methylsulfanyl-phenoxy)-phenyl]-hydrazono}-3-ethoxycarbonylamino-3-oxo-propionyl)-carbamic acid ethyl ester 
• 69360-51-6 4-[4-(Methylthio)-phenylthio]-phenylhydrazonomalonyldiurethan 
• 69360-52-7 4-[3-Methyl-4-(methylthio)-phenoxy]-phenylhydrazonomalonyldiurethan 
• 69360-61-8 3,5-Dichlor-4-[4-(methylthio)-phenoxy]-phenylhydrazonomalonyldiurethan 
• 69360-62-9 3,5-Dichlor-4-[4-(methylthio)-phenylthio]-phenylhydrazonomalonyldiurethan 
• 69360-77-6 4-Methylthio-phenylhydrazonomalonyldiurethan 
• 69360-41-4 4-[4-(Methylthio)-phenoxy]-phenylhydrazonomalonyldimethan 
• 108-13-4 malonodiamide 
• 51-79-6 urethane 

Relevant academic research and scientific papers

Herbicidal combinations containing 2-?(4-heterocyclic-phenoxymethyl)phenoxy!alkanoates

Herbicidal compositions containing herbicidal 2-?(4-heterocyclic-phenoxymethyl)phenoxy!alkanoates in combination with other herbicides are disclosed. The herbicidal 2-?(4-heterocyclic-phenoxymethyl)phenoxy!-alkanoates are of the formula STR1 in which R' is methyl, W is oxygen, Q is STR2 R is hydrogen, M, lower alkyl; cycloalkyl comprising from 3 to 6 carbon atoms; lower alkenyl; or lower alkynyleach optionally substituted with one or more chlorine or fluorine, or --?CHR7 --(CH2)m O!n R8 ; each of R1 through R5 is lower alkyl or lower haloalkyl; R6 is lower alkyl, lower haloalkyl, lower cyano-alkyl, lower alkoxyalkyl, lower alkoxycarbonylalkyl, lower arylalkyl, or amino; R7 is hydrogen or methyl; R8 is lower alkyl; X is hydrogen, methyl, fluorine, or chlorine; Y is hydrogen; Z is hydrogen, fluorine, chlorine, bromine, lower alkyl, or methoxy; Z' is hydrogen, fluorine, or chlorine; Z and Z' taken together may be --(CH2)4 -- to form a tetrahydronaphthyl moiety; m is 0 to 2, and n is 1 to 6; and M is sodium, potassium or ammonium. These herbicidal alkanoates are used with either grass-controlling or broadleaf herbicides.

Herbicidal 2-[(4-heterocyclic-phenoxymethyl)phenoxy]-alkanoates

Herbicidal compounds, compositions containing them, and a method for controlling weeds by application of the compositions are disclosed. The herbicidal compounds are 2-[(4-heterocyclic-phenoxymethyl)phenoxy]alkanoates of the formula STR1 in which A is a derivative of an alkanoate bonded to the phenoxy oxygen at the alpha carbon, and Q is 4-difluoromethyl-4,5-dihydro-3-methyl-l,2,4-triazol-5(1H)-on-1-yl, 3,4,5,6-tetrahydrophthalimid-1-yl, 1-(1-methylethyl)imidazolidin-2,4-dion-3-yl, 1,4-dihydro-4-(3-fluoropropyl)-5H-tetrazol-5-on-1-yl, 3-chloro-4,5,6,7-tetrahydroindazol-2-yl, 4-methyl-l,2,4-triazine-3,5-dion-2-yl, 8-thia-1,6-diazabicyclo[4.3.0]-nonane-7-on-9-ylimino, or 1-methyl-6-trifluoromethyl-2,4-pyrimidinedione-3-yl; X is hydrogen, methyl, fluorine, or chlorine; Y is hydrogen; W is oxygen or sulfur; Z is hydrogen, fluorine, chlorine, bromine, lower alkyl, or methoxy; Z' is hydrogen, fluorine, or chlorine; and the group AO-- may be in the 2, 3, or 4-position of the phenyl ring.

Herbicical 2-[(4-heterocyclic-phenoxymethyl)phenoxy]-alkanoates

Herbicidal compounds, compositions containing them, and a method for controlling weeds by application of the compositions are disclosed. The herbicidal compounds are 2-[(4-heterocyclic(phenoxymethyl)phenoxy]alkanoates of the formula STR1 in which A is a derivative of an alkanoate bonded to the phenoxy oxygen at the alpha carbon, and Q is 4-difluoromethyl-4,5-dihydro-3-methyl-1,2,4-triazol-5(1H)-on-1-yl, 3,4,5,6-tetrahydrophthalimid-1-yl, 1-(1-methylethyl)imidazolidin-2,4-dion-3-yl, 1,4-dihydro-4-(3-fluoropropyl)-5H-tetrazol-5-on-1-yl, 3-chloro-4,5,6,7-tetrahydroindazol-2-yl, 4-methyl-1,2,4-triazine-3,5-dion-2-yl, 8-thia-1,6-diazabicyclo[4.3.0]nonane-7-on-9-ylimino, or 1-methyl-6-trifluoromethyl-2,4-pyrimidinedione-3-yl; X is hydrogen, fluorine, or chlorine; Y is hydrogen; W is oxygen or sulfur; Z is hydrogen, fluorine, chlorine, bromine, lower alkyl, or methoxy; Z' is hydrogen, fluorine, or chlorine; and the group AO-- may be in the 2, 3, or 4-position of the phenyl ring.

Purines, Pyrimidines and Imidazoles. Part 66. New Syntheses of Some Uridine and N-Alkoxycarbonyl 5-carboxamides, N-carbamoyl 5-carboxamides and 5-carboxamides

Ethoxymethylene-N,N'-(methoxy-, ethoxy- and benzyloxy-carbonyl)malonamides have been prepared from the corresponding N,N'-alkoxycarbonylmalonamides with triethyl orthoformate and acetic anhydride.The three ethoxymethylene derivatives with primary alkyl- o

Purines, Pyrimidines, and Imidazoles. Part 60. Some Oxazolopyrimidines and a Novel Conversion of a Cyanouracil into a Barbituric Acid Derivative

The synthesis of several 6-acetyl(or 6-cyano)-2,3-dihydro-7-oxo-7H-oxazolopyrimidines (1) from 5-acetyl(or 5-cyano)-1-uracils and 5-acetyl(or 5-cyano, or 5-cinnamoyl, or 5-N-ethoxycarbonylcarbamoyl)-1-(1-ethyl-2-hydroxyethyl)uracils (2) by cyclisation of their toluene-4-sulphonates or methanesulphonates with triethylamine is described.The reaction of 6-cyano-1-(1-ethyl-2-hydroxyethyl)-2,3-dihydro-7-oxo-7H-oxazolopyrimidine (1e) with cyclohexylamine produced 5-amino-6-cyclohexyliminomethyl-1-ethyl-2,3-dihydro-7-oxo-7H-oxazolopyrimidine (6a) which with hot water gave ammonia and 5-cyclohexylaminomethylene-1-(1-ethyl-2-hydroxyethyl)barbituric acid (7a).Similar reactions occurred with butylamine and benzylamine and with related oxazolopyrimidines, but in contrast compound (1e) and morpholine gave the isocytosine (11).The structures assigned were confirmed by the synthesis of the acid (7a) and of the related 5-cyclohexylaminomethylene-1-methylbarbituric acid and by 1H n.m.r., i.r., u.v., and mass spectroscopy.