49797-11-7

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 104-86-9 4-chlorobenzylamine 
• 719-64-2 5-chloro-3-phenylanthranil 
• 195066-98-9 2-(p-chlorobenzoyl)-5-chlorobenzophenone 

Downstream Products

• 128889-33-8 6-Amino-2-(p-aminophenyl)-4-phenylquinazoline 

Relevant academic research and scientific papers

Fe3O4@Sap/Cu(ii): An efficient magnetically recoverable green nanocatalyst for the preparation of acridine and quinazoline derivatives in aqueous media at room temperature

Saponin, as a green and available phytochemical, was immobilized on the surface of magnetite nanoparticles then doped with Cu ions (Fe3O4@Sap/Cu(ii)) and used as an efficient nanocatalyst for the synthesis of quinazoline and acridine derivatives, due to t

A new triazine-cored covalent organic polymer for catalytic applications

A triazine based covalent organic polymer (CC-TAPT-COP) was designed and synthesized via nucleophilic substitution reaction between 1,3,5-tris-(p-aminophenyl) triazine and cyanuric chloride under refluxing conditions with bottom-up approach. The structura

A convenient access to 2,4-disubstituted quinazolines via one-pot three-component reaction under mild conditions?

A new and practical method has been developed for the synthesis of 2,4-disubstituted quinolines via one-pot three-component reaction of o-amino arylketones, aldehydes and ammonium acetate in high yields by using DDQ in CH3CN under mild conditio

Synthesis of Quinazoline and Quinazolinone Derivatives via Ligand-Promoted Ruthenium-Catalyzed Dehydrogenative and Deaminative Coupling Reaction of 2-Aminophenyl Ketones and 2-Aminobenzamides with Amines

The in situ formed ruthenium catalytic system ([Ru]/L) was found to be highly selective for the dehydrogenative coupling reaction of 2-aminophenyl ketones with amines to form quinazoline products. The deaminative coupling reaction of 2-aminobenzamides with amines led to the efficient formation of quinazolinone products. The catalytic coupling method provides an efficient synthesis of quinazoline and quinazolinone derivatives without using any reactive reagents or forming any toxic byproducts.

Synthesis of quinazolines over recyclable Fe3O4@SiO2-PrNH2-Fe3+ nanoparticles: A green, efficient, and solvent-free protocol

A practical and efficient method is developed for efficient synthesis of quinazoline derivatives through condensation reaction of 2-aminoaryl ketone, an aldehyde, and ammonium acetate, over magnetic Fe3O4@SiO2-PrNH2/

Efficient synthesis of quinazoline derivatives catalyzed by flourinated alcohol

A facile and efficient protocol is reported for the synthesis of quinazoline derivatives via a one-pot multicomponent reaction of 2-amino-5-chlorobenzophenone, aromatic aldehydes and ammonium acetate using 1,1,1,3,3,3-hexafluoroisopropanol (HFIP). The use

A new and facile CuCl2·2H2O-catalyzed one-pot three-component synthesis for quinazolines

A new and facile CuCl2·2H2O-catalyzed one-pot three-component synthesis for quinazolines has been developed. A mixture of readily available 2-amino-5-chlorobenzophenones, substituted benzaldehydes, ammonium acetate, and CuCl2/s

Recyclable, magnetic ionic liquid bmim[FeCl4]-catalyzed, multicomponent, solvent-free, green synthesis of quinazolines

An atom-efficient, eco-friendly, solvent-free, high yielding, multicomponent green strategy to synthesize highly functionalized quinazoline derivatives by the one-pot reaction of 2-aminobenzophenone, aromatic aldehyde and ammonium acetate is presented. Ma

Recyclable graphite oxide promoted efficient synthesis of 2-phenyl quinazoline derivatives in the presence of TBHP as an oxidant

A novel and efficient protocol for the synthesis of 2-phenyl quinazoline derivatives is developed by recyclable graphite oxide as a catalyst, devoid of moisture sensitive metal catalysts and corrosive acidic reagents. This new procedure has afforded the desired products in good to excellent yields. The graphite oxide can be synthesized by a simple adoptable procedure from inexpensive and readily available graphite and is recoverable and reusable up to four cycles, without any loss of activity.

I2-Catalyzed three-component protocol for the synthesis of quinazolines

An efficient and one-pot three-component strategy for synthesizing highly functionalized quinazoline derivatives is presented. A mixture of 2-aminobenzophenone, aromatic aldehyde and ammonium acetate in the presence of I2-catalyst provides desired product