499136-63-9

Upstream product

• 100-39-0 benzyl bromide 
• 499136-62-8 2-(2-{2-[2-((R)-2,2-Dimethyl-[1,3]dioxolan-4-ylmethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol 
• 477781-69-4 1-phenyl-2,5,8,11-tetraoxatridecan-13-yl methanesulfonate 
• 14347-78-5 1,2-O-isopropylidene-D-glycerol 
• 112-60-7 Tetraethylene glycol 
• 23735-43-5 (S)-1-O-tosyl-2,3-O-isopropylideneglycerol 

Downstream Products

• 499136-64-0 (2S)-17-phenyl-4,7,10,13,16-pentaoxapentadecane-1,2-diol 

Relevant academic research and scientific papers

Archaea analogue thiolipids for tethered bilayer lipid membranes on ultrasmooth gold surfaces

Simple vesicle fusion allowed the formation of a bilayer lipid membrane from the self-assembled monolayer of lipoic acid ester 1 (see formula). Film thicknesses determined by surface plasmon resonance (SPR) spectroscopic measurements agree with the theore

New deuterated oligo(ethylene glycol) building blocks and their use in the preparation of surface active lipids possessing labeled hydrophilic tethers

(Chemical Equation Presented) For the introduction of additional analysis protocols of tethered molecules, a method is presented to prepare functionalized, deuterated oligo(ethylene glycols) from ethylene glycol-d 4. Partial oligomerization of ethylene glycol-d4 and conversion to ditosylates is accompanied by coupling reactions to prepare doubly benzyl protected oligo(ethylene glycols) with two to five repeating units. The tetramer bearing 16 deuteria was elaborated at both ends to eventually prepare 2,3-di-O-phytanyl-sn-glycerol-1-tetraethylene glycol-D,L-α-lipoic acid ester (DPTL), which bears a fully deuterated tetra(ethylene glycol) spacer group. Through linking of functionalized components, an analogue of DPTL possessing an octa(ethylene glycol) spacer group was prepared, both in deuterated and unlabeled form.