499203-35-9Relevant academic research and scientific papers
Synthesis, conformation and antiviral activity of nucleoside analogues with the (2-hydroxy-1-phenylethoxy)methyl glycone - A family of nucleoside analogues related to d4T and aciclovir
Ewing, David F.,Glacon, Virginie,Len, Christophe,Mackenzie, Grahame
, p. 1461 - 1468 (2007/10/03)
A complete family of acyclic nucleoside analogues has been obtained by combining the (2-hydroxy-1-phenylethoxy)methyl glycone with the nucleoside bases adenine, guanine, cytosine, thymine and uracil. In each case both optical antipodes have been prepared
Asymmetric synthesis of both enantiomers of two acyclic nucleoside analogues related to d4T and acyclovir
Ewing, David F,Gla?on, Virginie,Mackenzie, Grahame,Len, Christophe
, p. 989 - 991 (2007/10/03)
The enantiomers of 1-{[(2-hydroxy-1-phenyl)ethoxy]methyl}thymine and 9-{[(2-hydroxy-1-phenyl)ethoxy]methyl}guanine have been obtained in high yield in five steps from (R)- and (S)-1-phenylethan-1,2-diol. These chiral compounds are acyclic nucleoside analo
