289625-33-8

Basic information

• Product Name: 1,2-Ethanediol, 1-phenyl-, 2-benzoate, (1R)-
• CAS NO: 289625-33-8
• Molecular Formula: C15H14O3
• Molecular Weight: 242.274
• Mol File: 289625-33-8.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediol, 1-phenyl-, 2-benzoate, (1R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediol, 1-phenyl-, 2-benzoate, (1R)-(289625-33-8)
• EPA Substance Registry System: 1,2-Ethanediol, 1-phenyl-, 2-benzoate, (1R)-(289625-33-8)

Safety Data

• Hazardous Substances Data: 289625-33-8(Hazardous Substances Data)

Upstream product

• 33868-50-7 phenacyl benzoate 
• 16355-00-3 (R)-1-phenyl-1,2-ethanediol 
• 501-53-1 benzyl chloroformate 
• 93-56-1 phenylethane 1,2-diol 
• 100-52-7 benzaldehyde 
• 98-86-2 acetophenone 
• 98-88-4 benzoyl chloride 

Downstream Products

• 871118-07-9 (R)-[2-(acetoxymethoxy)-2-phenyl]ethyl benzoate 
• 499203-35-9 (R)-9-[(2-benzoyloxy-1-phenylethoxy)methyl]guanine 
• 499203-31-5 (R)-1-[(2-benzoyloxy-1-phenylethoxy)methyl]thymine 
• 499203-34-8 (R)-9-[(2-benzoyloxy-1-phenylethoxy)methyl]adenine 
• 499203-33-7 (R)-1-[(2-benzoyloxy-1-phenylethoxy)methyl]cytosine 
• 499203-32-6 (R)-1-[(2-benzoyloxy-1-phenylethoxy)methyl]uracil 
• 871118-06-8 (R)-[2-(methoxymethoxy)-2-phenyl]ethyl benzoate 

Relevant articles and documents

Kinetic Resolution of 1,2-Diols via NHC-Catalyzed Site-Selective Esterification

A kinetic resolution of 1,2-diols bearing both a secondary and a primary alcohol motif through an N-heterocyclic carbene-catalyzed oxidative acylation reaction has been developed. A site- and enantioselective esterification reaction is involved for this process. Both the monoacylated diols obtained and the remaining enantioenriched 1,2-diols are versatile building blocks for the preparation of functional molecules with proven biological activities.

Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1- arylethanones

First hand: The first example of a palladium-catalyzed asymmetric hydrogenation of α-acyloxy ketones (1) was accomplished to give the hydrogenated products 2 with by far the highest catalytic efficiency in up to quantitative conversions and excellent enantioselectivities. The hydrogenated products could serve as important intermediates for the preparation of many drug candidates. TFE=2,2,2-trifluoroethanol. Copyright

Kinetic resolution of diols and pyridyl alcohols by cu(II)(borabox)- catalyzed acylation

Boron-bridged bisoxazoline (borabox) ligands have been used in the copper(II)-catalyzed benzoylation of pyridyl alcohols and 1,2-diols. Efficient kinetic resolution of 1,2-diols was achieved using both borabox and bisoxazoline (box) ligands. Borabox ligands induced high selectivities in the benzoylation of suitable pyridyl alcohols, where they outperformed bisoxazolines. In addition, highly enantioselective Cu(II)(borabox)-catalyzed benzoylation has been used for the synthesis of both enantiomers of a pyridyl alcohol.