4995-12-4

Basic information

• Product Name: 2-(4-Methoxyphenyl)pyrrole
• Synonyms: 2-(4-Methoxyphenyl)pyrrole;1H-Pyrrole, 2-(4-methoxyphenyl)-
• CAS NO: 4995-12-4
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 173.21114
• Mol File: 4995-12-4.mol
• Article Data: 26

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Methoxyphenyl)pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)pyrrole(4995-12-4)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)pyrrole(4995-12-4)

Safety Data

• Hazardous Substances Data: 4995-12-4(Hazardous Substances Data)

Usage

Description

2-(4-Methoxyphenyl)pyrrole, also known as 4-Methoxyphenyl-2-pyrrole, is a heterocyclic chemical compound characterized by a pyrrole ring with a 4-methoxyphenyl group attached to it. This unique molecular structure endows it with potential applications in organic synthesis, pharmaceutical research, and agriculture due to its distinctive properties.

Uses

Used in Organic Synthesis:
2-(4-Methoxyphenyl)pyrrole is used as a building block for the synthesis of various organic compounds, leveraging its heterocyclic nature to contribute to the formation of complex molecular structures.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(4-Methoxyphenyl)pyrrole is utilized as a key component in the development of new drugs, owing to its potential medicinal properties which are currently under investigation.
Used as a Pesticide:
2-(4-Methoxyphenyl)pyrrole is being studied for its potential use as a pesticide, capitalizing on its reported insecticidal activity to offer a new option for agricultural pest control.

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 2475-92-5 4-methoxyacetophenone oxime 
• 107-06-2 1,2-dichloro-ethane 
• 2475-92-5 (E)-1-(4-methoxyphenyl)ethanone oxime 
• 56139-60-7 1-(4-Methoxyphenyl)-1,4-butandion 
• 109-97-7 pyrrole 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 1963-36-6 4-methoxycinnamaldehyde 
• 4995-06-6 4-Nitro-1-(4-methoxy-phenyl)-butadien-(1,3) 
• 22217-80-7 2-(4-methoxyphenyl)-1-pyrroline 
• 696-62-8 para-iodoanisole 
• 115298-63-0 phenyl(4-methoxyphenyl)iodonium triflate 

Downstream Products

• 91735-79-4 2-(4-methoxyphenyl)-5-trifluoroacetylpyrrole 
• 431039-10-0 5-(4-methoxyphenyl)-1H-pyrrole-2-carbaldehyde 
• 1604834-10-7 C₂₃H₂₂N₂O₂ 
• 1497397-05-3 C₂₅H₂₄BF₂N₃O₃ 

Relevant articles and documents

Fabrication of Graphitic Carbon Nitride-Based Film: An Emerged Highly Efficient Catalyst for Direct C—H Arylation under Solar Light

Photoredox C—H bond formation can proceed in aerobic environment under solar light and has therefore become attractive. Nowadays, different types of expensive novel metal complexes and nanomaterials have been urbanized as photocatalysts for direct C—H bon

Isomer-Specific Hydrogen Bonding as a Design Principle for Bidirectionally Quantitative and Redshifted Hemithioindigo Photoswitches

A new class of bidirectionally quantitative photoswitches based on the hemithioindigo (HTI) scaffold is reported. Incorporation of a pyrrole hydrogen-bond donor leads to a bathochromic shift allowing for quantitative bidirectional isomerization. Additionally, extending conjugation from the electron-rich pyrrole results in quantitative visible-light photoswitches, as well as photoswitches that isomerize with red and near-infrared light. The presence of the hydrogen bond leading to the observed redshift is supported by computational and spectroscopic evidence.

Direct synthesis of aryl substituted pyrroles from calcium carbide: An underestimated chemical feedstock?

In this work, a novel synthetic methodology for the preparation of aryl pyrroles directly from the reaction of calcium carbide with oxime is reported. Various pyrrole derivatives are generated from the corresponding oximes in satisfactory yields (49–88%) under the optimized conditions. The one-pot synthesis of aryl pyrrole from widely available ketone is also successfully developed. A new near-infrared fluorescent BODIPY dye containing a phenyl substitution at the C-3 position is expediently prepared from the aryl pyrrole derived from this methodology. The key benefit of this methodology is the use of an inexpensive and less hazardous primary chemical feedstock, calcium carbide, in a wet solvent without any metal catalysts. This process offers a novel cost-efficient route for the synthesis of functionalized pyrrole.