499781-40-7Relevant academic research and scientific papers
Total synthesis of newbouldine via reductive N-N bond formation
Pangerl, Michael,Hughes, Chambers C.,Trauner, Dirk
experimental part, p. 6626 - 6631 (2010/10/19)
The first total synthesis of newbouldine has been achieved employing a new, reductive N-N bond forming reaction. The asymmetric synthesis confirms that the natural product is a racemate.
Total synthesis of (-)-amathaspiramide F
Sakaguchi, Kazuhiko,Ayabe, Miki,Watanabe, Yusuke,Okada, Takuya,Kawamura, Kazushige,Shinada, Tetsuro,Ohfune, Yasufumi
scheme or table, p. 10355 - 10364 (2010/03/03)
The stereoselective total synthesis of the marine alkaloid, (-)-amathaspiramide F (1), was achieved from the α-hydroxy-α-ethynylsilane 2. The key steps involved in the synthesis were (1) the enolate Claisen rearrangement of the α-acyloxy-α-alkenylsilane f
Total synthesis of (-)-amathaspiramide F
Sakaguchi, Kazuhiko,Ayabe, Miki,Watanabe, Yusuke,Okada, Takuya,Kawamura, Kazushige,Shiada, Tetsuro,Ohfune, Yasufumi
supporting information; experimental part, p. 5449 - 5452 (2009/06/20)
(Chemical Equation Presented) The stereoselective total synthesis of the marine alkaloid (-)-amathaspiramide F (1) was achieved from the α-hydoxy-α-ethynylsilane 2. The crucial steps in this synthesis involved not only the enolate Claisen rearrangement of
The total synthesis of (-)-amathaspiramide F
Hughes, Chambers C.,Trauner, Dirk
, p. 4556 - 4559 (2007/10/03)
Breaking the cis rule: L-Proline and not as expected D-proline led to (-)-amathaspiramide F with the correct configuration in a short sequence of steps (see retrosynthetic scheme). This synthesis features an exception to the principle of self-regeneration
