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500011-92-7 Usage


ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLATE is a pyrazole derivative with the molecular formula C10H8BrClN3O2. It is a chemical compound that features bromine, chlorine, and carboxylate functional groups, making it a versatile building block in organic synthesis and pharmaceutical research.
Used in Pharmaceutical Research:
ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLATE is used as a building block for the preparation of novel pyrazole-based compounds with potential biological activities. Its unique structure and functional groups contribute to the development of new drugs with therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLATE serves as a valuable intermediate for the creation of various chemical entities. Its presence of bromine and chlorine atoms allows for further functionalization and the synthesis of complex organic molecules.
Used in Agrochemical Development:
ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLATE is also utilized in the development of new agrochemicals. Its potential to form biologically active compounds makes it a candidate for use in the creation of pesticides or other agricultural chemicals to improve crop protection and yield.
Safety Note:
It is crucial to handle ETHYL 3-BROMO-1-(3-CHLOROPYRIDIN-2-YL)-1H-PYRAZOLE-5-CARBOXYLATE with care and adhere to proper safety protocols to minimize health risks associated with its use and storage.

Check Digit Verification of cas no

The CAS Registry Mumber 500011-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,0,0,1 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 500011-92:
67 % 10 = 7
So 500011-92-7 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017


1.1 GHS Product identifier

Product name ethyl 5-bromo-2-(3-chloropyridin-2-yl)pyrazole-3-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:500011-92-7 SDS

500011-92-7Relevant articles and documents

Diamides conformationally restricted with central amino acid: Design, synthesis, and biological activities

Chen, Rui-Jia,Cheng, Jia-Gao,Dong, Le-Feng,Feng, Ting-Ting,Gu, Yu-Cheng,Li, Zhong,Shao, Xu-Sheng,Wang, Gang-Ao,Wang, Jun-Jie,Xu, Xiao-Yong,Xu, Zhi-Ping,Zhou, Cong

, (2022/02/03)

Diamide insecticides, represented by chlorantraniliprole (CHL), were widely applied in the control of lepidopteran insects. In efforts to develop bioactive diamides with novel scaffolds, we design and synthesized a series of diamides containing central amino acids to conformationally simulate CHL. Bioassay results indicated that most compounds containing 1-aminocyclopropane-1-carboxylic acid exhibited excellent larvacidal potency against Mythimna separate and Plutella xylostella. After a systematic structure–activity relationship study, 1–23 was identified as a potential insecticidal candidate with LC50 values of 34.920 mg·L?1 against M. separate and 61.992 mg·L?1 on P. xylostella. Finally, molecular docking revealed the possible binding mode of 1–23 with the target protein, ryanodine receptors.



Page/Page column 10-13, (2021/02/26)

Disclosed a method for preparing compound of Formula (I) and (II) wherein R1, R2, R3, X and n are as defined in the disclosure.

Design, synthesis, and insecticidal activities of novel diamide derivatives with alpha-amino acid subunits

Chen, Rui-Jia,Wang, Jun-Jie,Han, Li,Gu, Yu-Cheng,Xu, Zhi-Ping,Cheng, Jia-Gao,Shao, Xu-Sheng,Xu, Xiao-Yong,Li, Zhong

, p. 1429 - 1436 (2021/05/06)

A series of diamide derivatives containing α-amino acids were designed and synthesized. These compounds were evaluated for their insecticidal activities against Plutella xylostella, Mythimna separate, Myzus persicae, and Tetranychus cinnabarinus. Most of the title compounds containing an l-phenylglycine skeleton were endowed with good activities at the concentration of 500 mg·L?1. Compounds (R)-A6 showed a potential value for further optimization as an insecticidal lead with the LC50 value of 86.8 mg·L?1.

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