500102-62-5

Basic information

• Product Name: 2-Propenoic acid, 3-(4-fluoro-2-methylphenyl)-, ethyl ester, (2E)-
• CAS NO: 500102-62-5
• Molecular Formula: C12H13FO2
• Molecular Weight: 208.232
• Mol File: 500102-62-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(4-fluoro-2-methylphenyl)-, ethyl ester, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(4-fluoro-2-methylphenyl)-, ethyl ester, (2E)-(500102-62-5)
• EPA Substance Registry System: 2-Propenoic acid, 3-(4-fluoro-2-methylphenyl)-, ethyl ester, (2E)-(500102-62-5)

Safety Data

• Hazardous Substances Data: 500102-62-5(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 63082-45-1 4-fluoro-2-methylbenzaldehyde 
• 452-63-1 2-Bromo-5-fluorotoluene 
• 6163-58-2 tris-(o-tolyl)phosphine 
• 140-88-5 ethyl acrylate 

Downstream Products

• 850794-14-8 C₃₃H₂₉F₃O₅ 
• 166251-34-9 3-(4-fluoro-2-methylphenyl)propionic acid 
• 174603-42-0 6-fluoro-4-methyl-1-indanone 
• 174603-41-9 ethyl 3-(4-fluoro-2-methylphenyl)propionate 

Relevant articles and documents

Method for synthesizing photoactive bromohydrin compound

The invention discloses a method for synthesizing a photoactive bromohydrin compound, which comprises the following steps: reacting cinnamyl alcohol as shown in a formula I, benzamide bromide as shown in a formula II, a quinine derivative, L-camphorsulfonic acid and water in a first organic solvent to obtain the bromohydrin compound as shown in a formula III. According to the method, raw materials are easy to synthesize, reaction conditions are mild, operation is easy and convenient, the yield reaches up to 47%-87%, enantioselectivity can generally reach 80% or above, and the highest point can even reach 95%.

NRF2 REGULATORS

The present invention relates to bis aryl analogs, pharmaceutical compositions containing them and their use as Nrf2 regulators.

Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity

Extension of the structure-activity relationship studies that led to the discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1, has given rise to (E)-2-(4-chloro-6-fluoro