500127-41-3Relevant articles and documents
Successive substitution of halogen atoms in 4,6-dihaloquinolines in palladium-catalyzed reactions with amines and arylboronic acids
Beletskaya,Tsvetkov,Tsvetkov,Latyshev,Lukashev
, p. 215 - 219 (2005)
A procedure was developed for the synthesis of 4,6-diamino- and 4,6- or 6,4-arylaminoquinolines by palladium-catalyzed C-N- and/or C-C-cross-coupling of 6-bromo-4-chloroquinoline.
Successive replacement of halogen atoms in 4,6-dihaloquinolines in cross-coupling reactions with arylboronic acids catalyzed by palladium and nickel complexes
Beletskaya,Tsvetkov,Latyshev,Lukashev
, p. 1660 - 1667 (2003)
Conditions were found where in 6-halo-4-quinolines (halogen = iodine, bromine, or chlorine) the halogen atoms were replaced in succession by similar or different aryl groups in cross-coupling reactions with arylboric acids catalyzed by palladium and nickel complexes. Basing on successive Suzuki reaction a convenient procedure was developed for preparation of diarylquinolines that did not require isolation of the intermediate monoarylation product and afforded almost quantitative yields of diarylquinolines.
The successive substitution of halogens in 4-chloro-6-iodoquinoline by aryl groups in cross-coupling reactions with arylboronic acids
Tsvetkov, Alexey V.,Latyshev, Gennadij V.,Lukashev, Nikolai V.,Beletskaya, Irina P.
, p. 7267 - 7270 (2007/10/03)
The conditions for selective stepwise substitution of iodine and chlorine atoms in 4-chloro-6-iodoquinoline which allow the synthesis of the corresponding diarylquinolines with different aryl groups in the 4- and 6-positions, in a one-pot procedure, in hi
