500214-46-0Relevant articles and documents
METHODS FOR TREATING GASTRIC AND PANCREATIC MALIGNANCIES
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, (2012/02/13)
The invention provides methods and pharmaceutical compositions for treating pancreatic cancer or gastric cancer or a metastasis thereof.
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity
Ruchelman, Alexander L.,Singh, Sudhir K.,Ray, Abhijit,Wu, Xiao Hua,Yang, Jin-Ming,Li, Tsai-Kun,Liu, Angela,Liu, Leroy F.,LaVoie, Edmond J.
, p. 2061 - 2073 (2007/10/03)
5H-Dibenzo[c,h]1,6-naphthyridine-6-ones can exhibit potent antitumor activity. The effect of varied substituents at the 5-position of 5H-8,9-dimethoxy-2,3-methylenedioxydibenzo[c,h]1,6-naphthyridine on relative cytotoxicity and topoisomerase I-targeting a