500701-36-0

Basic information

• Product Name: METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE
• Synonyms: METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE;1H-IMidazole-2-carboxylic acid, 4-[[(1,1-diMethylethoxy)carbonyl]aMino]-1-Methyl-, Methyl ester;methyl 4-[(tert-butoxycarbonyl)amino]-N-methyl-1H-imidazole-2-carboxylate;methyl 1-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]imidazole-2-carboxylate
• CAS NO: 500701-36-0
• Molecular Formula: C11H17N3O4
• Molecular Weight: 255.27
• Mol File: 500701-36-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE(500701-36-0)
• EPA Substance Registry System: METHYL 4-(TERT-BUTOXYCARBONYLAMINO)-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLATE(500701-36-0)

Safety Data

• Hazardous Substances Data: 500701-36-0(Hazardous Substances Data)

Usage

General Description

Methyl 4-(tert-butoxycarbonylamino)-1-methyl-1H-imidazole-2-carboxylate is a chemical compound with the molecular formula C13H19N3O4. It is a derivative of imidazole and is commonly used in organic synthesis as a building block for various pharmaceutical compounds and other organic molecules. The compound is a white to off-white solid and is soluble in organic solvents such as acetone, ethanol, and chloroform. It is important to handle this compound with care, as it can be harmful if ingested, inhaled, or comes into contact with skin or eyes.

Upstream product

• 500903-65-1 (2-chlorocarbonyl-1-methyl-1H-imidazol-4-yl)-carbamic acid tert-butyl ester 
• 30148-23-3 2-trichloroacetyl-1-methylimidazole 
• 120095-64-9 2,2,2-trichloro-1-(1-methyl-4-nitro-1H-imidazol-2-yl)ethan-1-one 
• 24424-99-5 di-tert-butyl dicarbonate 
• 169770-25-6 1-methyl-4-nitro-1H-imidazole-2-carboxylic acid methyl ester 

Downstream Products

• 162085-97-4 methyl 4-amino-1-methyl-1H-imidazole-2-carboxylate 
• 464892-44-2 4-(1-methylimidazole-2-carboxamido)-1-methylimidazole-2-carboxylic acid 
• 128293-64-1 4-[(tert-butoxycarbonyl)amino]-1-methylimidazole-2-carboxylic acid 

Relevant articles and documents

Synthesis of N-methylpyrrole and N-methylimidazole amino acids suitable for solid-phase synthesis

New and higher yielding synthetic routes to N-protected N-methylpyrrole and N-methylimidazole amino acids are introduced to circumvent difficulties associated with established schemes. Key steps in each synthesis include copper-mediated cross-coupling reaction to directly install a carbamate-protected 4-amine in the N-methylpyrrole derivative and effective nitration followed by a one-pot reduction/Boc protection of the amine in the synthesis of the N-Me-imidazole amino acid.

Aromatic and heteroaromatic acid halides for synthesizing polyamides

The present invention is directed to protected amino acid halide monomers and oligomers, and to their use in the efficient sythesis of polyamides. The present invention is further directed to the use of α-haloenamine reagents, which may optionally be immobilized, for the preparation of the amino acid halides.