500766-02-9

Basic information

• Product Name: 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-ol
• Synonyms: 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-ol
• CAS NO: 500766-02-9
• Molecular Weight: 400.544
• Mol File: 500766-02-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-ol(500766-02-9)
• EPA Substance Registry System: 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-ol(500766-02-9)

Safety Data

• Hazardous Substances Data: 500766-02-9(Hazardous Substances Data)

Upstream product

• 500766-01-8 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-one 
• 247224-05-1 2-(2-benzylmercapto-4-phenyl-imidazol-1-yl)-1-phenyl-ethanone 
• 55796-74-2 (benzylsulfanyl)methanimidamide hydrobromide 
• 100-39-0 benzyl bromide 

Downstream Products

• 500766-03-0 1-phenyl-2-(4-phenyl-2-phenylmethanesulfonylimidazolyl)propan-1-ol 

Relevant articles and documents

Synthesis of novel 2,3-dihydroimidazo[2,1-b][1,3]oxazoles through intramolecular nucleophilic ipso-substitution in 2-alkylsulfonylimidazoles

Readily available 2-(benzylsulfanyl)imidazoles 6, were studied as potential precursors toward the synthesis of novel diversely substituted 2,3-dihydroimidazo[2,1-b][1,3]oxazoles. Thus, the reaction between enolates derived from 6 and different electrophiles as well as the addition of Grignard reagents to the carbonyl group in 6 were explored. The formation of the fused imidazoxazoles 20 under mild conditions was successfully accomplished taking advantage of the key role played by the 2-alkylsulfonyl moiety in 19 as an efficient leaving group in intramolecular nucleophilic ipso-substitution reactions.