247224-05-1

Basic information

• Product Name: Ethanone, 1-phenyl-2-[4-phenyl-2-[(phenylmethyl)thio]-1H-imidazol-1-yl]-
• CAS NO: 247224-05-1
• Molecular Formula: C24H20N2OS
• Molecular Weight: 384.502
• Mol File: 247224-05-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-phenyl-2-[4-phenyl-2-[(phenylmethyl)thio]-1H-imidazol-1-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-phenyl-2-[4-phenyl-2-[(phenylmethyl)thio]-1H-imidazol-1-yl]-(247224-05-1)
• EPA Substance Registry System: Ethanone, 1-phenyl-2-[4-phenyl-2-[(phenylmethyl)thio]-1H-imidazol-1-yl]-(247224-05-1)

Safety Data

• Hazardous Substances Data: 247224-05-1(Hazardous Substances Data)

Upstream product

• 6297-94-5 2-benzylsulfanyl-4-phenyl-1⁽³⁾H-imidazole 
• 70-11-1 α-bromoacetophenone 
• 538-28-3 S-benzylisothiourea hydrochloride 
• 100-39-0 benzyl bromide 
• 64-17-5 ethanol 
• 67-66-3 chloroform 

Downstream Products

• 247224-19-7 2-Benzylsulfanyl-4-phenyl-1-(2-phenyl-2-oxiranylmethyl)-1H-imidazole 
• 500766-11-0 1-(2-benzylsulfanyl-4-phenyl-imidazol-1-yl)-2-phenyl-propan-2-ol 
• 500766-05-2 2-(2-benzylsulfanyl-4-phenyl-imidazol-1-yl)-1,1-diphenyl-ethanol 
• 1322116-71-1 C₃₃H₂₈N₂O₂S 
• 500766-16-5 2-phenyl-1-(4-phenyl-2-phenylmethanesulfonyl-imidazol-1-yl)-propan-2-ol 
• 500766-03-0 1-phenyl-2-(4-phenyl-2-phenylmethanesulfonylimidazolyl)propan-1-ol 
• 500766-02-9 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-ol 
• 247224-14-2 1-phenyl-2-(4-phenyl-2-phenylmethanesulfonyl-imidazol-1-yl)-ethanol 
• 500766-01-8 2-(2-benzylsulfanyl-4-phenylimidazol-1-yl)-1-phenylpropan-1-one 
• 247224-11-9 2-(2-benzylsulfanyl-4-phenyl-imidazol-1-yl)-1-phenyl-ethanol 

Relevant articles and documents

Synthesis of novel 2,3-dihydroimidazo[2,1-b][1,3]oxazoles through intramolecular nucleophilic ipso-substitution in 2-alkylsulfonylimidazoles

Readily available 2-(benzylsulfanyl)imidazoles 6, were studied as potential precursors toward the synthesis of novel diversely substituted 2,3-dihydroimidazo[2,1-b][1,3]oxazoles. Thus, the reaction between enolates derived from 6 and different electrophiles as well as the addition of Grignard reagents to the carbonyl group in 6 were explored. The formation of the fused imidazoxazoles 20 under mild conditions was successfully accomplished taking advantage of the key role played by the 2-alkylsulfonyl moiety in 19 as an efficient leaving group in intramolecular nucleophilic ipso-substitution reactions.