500770-72-9

Basic information

• Product Name: BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID
• Synonyms: BOC-D-PHG(3-F)-(C*CH2)OH;BOC-BETA-PHE(3-F)-OH;BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPANOIC ACID;BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID;(S)N-T-BUTOXYCARBONYL-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID;(S)-3-TERT-BUTOXYCARBONYLAMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID;Boc-b-Phe(3-F)-OH;3-aMino-4-(tert-butoxy)-3-(3-fluorophenyl)-4-oxobutanoic acid
• CAS NO: 500770-72-9
• Molecular Formula: C₁₄H₁₈FNO₄
• Molecular Weight: 283.3
• EINECS: 200-258-5
• Product Categories: 3-Amino-3-phenylpropionic Acid Analogs;3-Amino-3-phenylpropanoic Acid Analogs;pharmacetical;B-Amino
• Mol File: 500770-72-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 422.1±40.0 °C(Predicted)
• Appearance: /
• Density: 1.214±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.26±0.10(Predicted)
• CAS DataBase Reference: BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID(500770-72-9)
• EPA Substance Registry System: BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID(500770-72-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 500770-72-9(Hazardous Substances Data)

Usage

General Description

BOC-(S)-3-amino-3-(3-fluoro-phenyl)-propionic acid is a chemical compound with the molecular formula C14H18FNO4. It is an amino acid derivative with a BOC (tert-butoxycarbonyl) protecting group attached to the amino group. BOC-(S)-3-AMINO-3-(3-FLUORO-PHENYL)-PROPIONIC ACID is a chiral molecule with a stereocenter at the alpha carbon, giving it S configuration. It is commonly used in organic synthesis and medicinal chemistry as a building block for the preparation of peptide and protein-based drugs. The presence of the fluorine substituent in the phenyl ring may impart specific biological and pharmacological properties to the compound. Overall, BOC-(S)-3-amino-3-(3-fluoro-phenyl)-propionic acid is an important chemical for the development of pharmaceuticals and biologically active compounds.

Upstream product

• 277745-38-7 (E)-3-(3-fluorophenyl)acrylic acid tert-butyl ester 
• 277745-39-8 tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-(3'-fluorophenyl)propanoate 

Downstream Products

• 376348-74-2 (S)-(1-(3-fluorophenyl)-3-oxopropyl)-carbamic acid tert-butyl ester 
• 528586-29-0 C₃₀H₄₂FN₃O₅S 

Relevant articles and documents

N-4-PIPERIDINYL COMPOUNDS AS CCR5 MODULATORS

The invention provides a compound of formula (I):[Chemical formula should be inserted here. Please see paper copy.] wherein R1, R2, R3, R3a, R4, R4a, R5, and R6 are as defined; or a pharmaceutically acceptable salt thereof or a solvate thereof; compositions containing these compounds, processes for preparing them and their use as modulators of chemokine activity (especially CCR5 activity).