528586-29-0

Upstream product

• 277745-38-7 (E)-3-(3-fluorophenyl)acrylic acid tert-butyl ester 
• 277745-39-8 tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-(3'-fluorophenyl)propanoate 
• 500770-72-9 (S)-[1-(3-fluoro-phenyl)-3-hydroxy-propyl]-carbamic acid tert-butyl ester 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 374725-41-4 N-(1-benzyl-piperidin-4-yl)-N-ethyl-2-(4-methanesulfonyl-phenyl)-acetamide 
• 374725-04-9 N-ethyl-2-(4-methanesulfonyl-phenyl)-N-piperidin-4-yl-acetamide 
• 376348-74-2 (S)-(1-(3-fluorophenyl)-3-oxopropyl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

N-4-PIPERIDINYL COMPOUNDS AS CCR5 MODULATORS

The invention provides a compound of formula (I):[Chemical formula should be inserted here. Please see paper copy.] wherein R1, R2, R3, R3a, R4, R4a, R5, and R6 are as defined; or a pharmaceutically acceptable salt thereof or a solvate thereof; compositions containing these compounds, processes for preparing them and their use as modulators of chemokine activity (especially CCR5 activity).