501037-04-3

Basic information

• Product Name: 2-Pentanone, 1,1,1-trifluoro-5-phenyl-, O-(phenylmethyl)oxime
• CAS NO: 501037-04-3
• Molecular Formula: C18H18F3NO
• Molecular Weight: 321.342
• Mol File: 501037-04-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Pentanone, 1,1,1-trifluoro-5-phenyl-, O-(phenylmethyl)oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentanone, 1,1,1-trifluoro-5-phenyl-, O-(phenylmethyl)oxime(501037-04-3)
• EPA Substance Registry System: 2-Pentanone, 1,1,1-trifluoro-5-phenyl-, O-(phenylmethyl)oxime(501037-04-3)

Safety Data

• Hazardous Substances Data: 501037-04-3(Hazardous Substances Data)

Upstream product

• 1821-12-1 4-Phenylbutyric acid 
• 501037-00-9 1-benzenesulfonyl-2,2,2-trifluoro-ethanone O-benzyl-oxime 
• 501036-99-3 N-benzyloxy-2,2,2-trifluoro-thioacetimidic acid phenyl ester 
• 501036-98-2 N-(benzyloxy)-2,2,2-trifluoroacetimidoyl chloride 
• 622-33-3 N-benzyloxyamine 
• 4119-41-9 1-iodo-3-phenylpropan 

Downstream Products

• 85674-68-6 1,1,1-trifluoro-5-phenyl-pentan-2-one 
• 122983-05-5 1,1,1-trifluoro-5-phenylpentan-2-amine 

Relevant articles and documents

Silver-Catalyzed Radical Transformation of Aliphatic Carboxylic Acids to Oxime Ethers

Oximes and oxime ethers are privileged building blocks and can be conveniently converted to ketones, amines, hydroxylamines, and nitriles. We describe the catalytic decarboxylation of aliphatic carboxylic acids to oxime ethers. With AgNO3 as the catalyst, valuable oxime ethers bearing various substituents could be easily obtained. The broad substrate scope, easy accessibility of aliphatic carboxylic acids, and mild reaction conditions make this strategy immediately applicable to the synthesis, late-stage functionalization, and modification of biologically active compounds. Experimental studies show the reaction undergoes a radical process.