501036-99-3

Upstream product

• 108-98-5 thiophenol 
• 501036-98-2 N-(benzyloxy)-2,2,2-trifluoroacetimidoyl chloride 
• 622-33-3 N-benzyloxyamine 
• 930-69-8 sodium thiophenolate 

Downstream Products

• 501037-03-2 1-adamantan-1-yl-2,2,2-trifluoro-ethanone O-benzyl-oxime 
• 501037-05-4 5-benzyloxy-1,1,1-trifluoro-pentan-2-one O-benzyl-oxime 
• 501037-01-0 1,1,1-trifluoro-6-phenoxy-hexan-2-one O-benzyl-oxime 
• 501037-02-1 1,1,1-trifluoro-3-methyl-5-phenyl-pentan-2-one O-benzyl-oxime 
• 501037-04-3 1,1,1-trifluoro-5-phenyl-pentan-2-one O-benzyl-oxime 
• 193202-41-4 1,1,1-Trifluoro-decan-2-one O-benzyl-oxime 
• 193202-45-8 2,2,2-Trifluoro-1-phenyl-ethanone O-benzyl-oxime 
• 22927-07-7 1,2-bis(4-tert-butylphenyl)ethane 
• 501037-00-9 1-benzenesulfonyl-2,2,2-trifluoro-ethanone O-benzyl-oxime 

Relevant academic research and scientific papers

Radical Transformation of Aliphatic C-H Bonds to Oxime Ethers via Hydrogen Atom Transfer

Herein, we describe a strategy for conversion of aliphatic C-H bonds to oxime ethers via hydrogen atom transfer. In this strategy, the decatungstate anion and sulfate radical play complementary roles in the abstraction of hydrogen atoms from primary, secondary, and tertiary C-H bonds of alkanes. The easy accessibility of alkanes and the broad substrate scope, mild conditions, and excellent regioselectivity of these reactions make this strategy applicable for the transformation of raw materials to high-value chemicals.

Radical-mediated synthesis of trifluoroethyl amines and trifluoromethyl ketones from alkyl iodides

Radical reaction of alkyl iodides with trifluoromethyl phenylsulfonyl oxime ether 10 and hexamethylditin at 300 nm in benzene afforded the corresponding trifluoromethyl oxime ethers 11 in high yields, which were reduced into the 2,2,2-trifluoroethyl amines with lithium aluminium hydride. The trifluoroethyl amines could be converted into the corresponding trifluoromethyl ketones by treatment with NBS and DBU.