501085-54-7Relevant articles and documents
Method for preparing vilazodone intermediate through copper-catalyzed coupling reaction
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Paragraph 0037; 0047-0049; 0056-0058; 0066-0068, (2021/08/07)
The invention discloses a method for preparing a vilazodone intermediate through a copper-catalyzed coupling reaction. The method comprises the following steps: step 1, generating 2-hydroxy-5-bromobenzene dimethyl acetal (IV) from 2-hydroxy-5-bromobenzald
Long-range diastereoselectivity in an Ugi reaction: Stereocontrolled and diversity-oriented synthesis of tetrahydrobenzoxazepines
Banfi, Luca,Bagno, Alessandro,Basso, Andrea,De Santis, Carlo,Riva, Renata,Rastrelli, Federico
, p. 5064 - 5075 (2013/11/06)
Salicylaldehydes and protected 1,2-amino alcohols have been convergently converted into a series of 2,3-dihydrobenzo[f][1,4]oxazepines, which undergo an Ugi-Joullie multicomponent reaction with unusual long-range diastereoselectivity. This protocol allows
RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME
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Page/Page column 20, (2010/11/28)
Disclosed herein are rhodanine derivatives, a method for the preparation thereof, and a pharmaceutical composition containing the same. The rhodanine derivatives have inhibitory activity against protein phosphatases (PPase) such as PTPlB, Prl-3, LAR, CD45