501085-54-7

Upstream product

• 1761-61-1 5-bromosalicyclaldehyde 
• 149-73-5 trimethyl orthoformate 
• 67-56-1 methanol 

Downstream Products

• 1761-61-1 5-bromosalicyclaldehyde 
• 944162-02-1 2-(2-(4-bromo-2-(dimethoxymethyl)phenoxy)ethyl)thiophene 
• 944162-11-2 t-butyl 2-(4-bromo-2-(dimethoxymethyl)phenoxy)ethylmethylcarbamate 
• 182344-24-7 3-formyl-4-hydroxyphenylboronic acid 
• 343306-50-3 4-(3-formyl-4-hydroxyphenyl)piperazine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Method for preparing vilazodone intermediate through copper-catalyzed coupling reaction

The invention discloses a method for preparing a vilazodone intermediate through a copper-catalyzed coupling reaction. The method comprises the following steps: step 1, generating 2-hydroxy-5-bromobenzene dimethyl acetal (IV) from 2-hydroxy-5-bromobenzald

Stereodivergent access to all four stereoisomers of chiral tetrahydrobenzo[f] [1,4]oxazepines, through highly diastereoselective multicomponent Ugi-Joullié reaction

Starting from easily accessible chiral enantiopure 1,2-amino alcohols and salicylaldehydes, a concise route to cyclic imines has been developed. These chiral cyclic imines undergo a highly diastereoselective Ugi-Joullié reaction to give trans tetrahydrobe

Long-range diastereoselectivity in an Ugi reaction: Stereocontrolled and diversity-oriented synthesis of tetrahydrobenzoxazepines

Salicylaldehydes and protected 1,2-amino alcohols have been convergently converted into a series of 2,3-dihydrobenzo[f][1,4]oxazepines, which undergo an Ugi-Joullie multicomponent reaction with unusual long-range diastereoselectivity. This protocol allows

Rhodanine Derivatives, a Process for the Preparation Thereof and Pharmaceutical Composition Containing the Same

Disclosed herein are rhodanine derivatives, a method for the preparation thereof, and a pharmaceutical composition containing the same. The rhodanine derivatives have inhibitory activity against protein phosphatases (PPase) such as PTP1B, Prl-3, LAR, CD45

RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Disclosed herein are rhodanine derivatives, a method for the preparation thereof, and a pharmaceutical composition containing the same. The rhodanine derivatives have inhibitory activity against protein phosphatases (PPase) such as PTPlB, Prl-3, LAR, CD45

Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.