501332-92-9Relevant academic research and scientific papers
A new synthesis of 6-substituted pyrido [2,3-d]pyrimidines
Kuwada, Takeshi,Harada, Kenichi,Nobuhiro, Junko,Choshi, Tominari,Hibino, Satoshi
, p. 2081 - 2090 (2007/10/03)
The reaction of the β-methylsulfanylacroleins, derived from alkenyl sulfides by the Vilsmeier reaction, with 6-aminouracils or 2,6-diaminouracil, provides a new synthetic route to the 6-substituted pyrido[2,3-d]pyrimidines by two methods, the reaction mec
Electrophilic behavior of lithiated 1-alkoxyalkyl and 1-alkylthioalkyl sulfones. Regioselective synthesis of enol ethers and vinyl sulfides
Habermann, Anne-Kathrin,Julia, Marc,Verpeaux, Jean-Noel,Zhang, Da
, p. 965 - 972 (2007/10/02)
The readily available 1-alkoxyalkyl and 1-alkylthioalkyl sulfones display electrophilic behavior when lithiated.For example, both react regioselectively with lithiated alkyl sulfones to give enol ethers and vinyl sulfides, respectively.A series of methyl and tert-butyl enol ethers and vinyl sulfides have been prepared. - Keywords: sulfones / alkoxyalkyl sulfones / carbenoids / enol ethers / heterosubstituted carbanions / alkylthioalkyl sulfones / vinyl sulfides
A CONVENIENT MATHOD FOR PREPARATION OF 1-(METHYLTHIO) AND 1-(PHENYLTHIO)VINYLLITHIUM REAGENTS
Takeda, Takeshi,Furukawa, Hiroyuki,Fujiwara, Tooru
, p. 593 - 596 (2007/10/02)
1-(Methylthio) and 1-(phenylthio)vinyllithiums were prepared by the treatment of the corresponding 2-methoxyethyl sulfides with twice molar amounts of butyllithium in the presence of N,N,N',N'-tetramethylethylenediamine (TMEDA). β-Alkylthio-β,γ-unsaturated alcohols were obtained in good yields by the reaction of the lithium salts with aldehydes.
