426833-07-0Relevant articles and documents
Enantioselective monoreduction of 2-alkyl 1,3-diketones using chiral ruthenium catalysts. Synthesis of the C14-C25 fragment of bafilomycin A 1
Eustache, Florence,Dalko, Peter I.,Cossy, Janine
, p. 8823 - 8826 (2007/10/03)
The enantioselective monoreduction of 2-alkyl 1,3-diketones by dynamic kinetic resolution using optically active ruthenium catalysts allowed the preparation of the C14-C25 fragment of bafilomycin A1.
Synthesis of the C14-C25 Subunit of Bafilomycin A1
Eustache, Florence,Dalko, Peter I.,Cossy, Janine
, p. 9994 - 10002 (2007/10/03)
The enantioselective synthesis of the C14-C25 subunit of bafilomycin A 1, was realized in a convergent route. The sequence involves two dynamic kinetic resolution steps of 2-alkyl 1,3-diketones that use optically active ruthenium complexes, an
Enantioselective Monoreduction of 2-Alkyl-1,3-diketones Mediated by Chiral Ruthenium Catalysts. Dynamic Kinetic Resolution
Eustache, Florence,Dalko, Peter I.,Cossy, Janine
, p. 1263 - 1265 (2007/10/03)
(Matrix Presented) The reduction of 2-alkyl-1,3-diketones using (R,R)- or (S,S)-RuCl[N-(tosyl)-1,2-diphenylethylenediamine](p-cymene) in the presence of formic acid and triethylamine affords syn-2-alkyl-3-hydroxy ketones as the major products with high en