502178-78-1Relevant articles and documents
ACETYL-COA SYNTHETASE 2 (ACSS2) INHIBITORS AND METHODS USING SAME
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Page/Page column 71-72, (2020/12/30)
The present disclosure provides compounds that are ACSS2 inhibitors. In certain embodiments, the compounds of the disclosure are useful for treating and/or preventing certain types of cancer.
QUINOXALINONE DERIVATIVES AS INSULIN SECRETION STIMULATORS, METHODS FOR OBTAINING THEM AND USE THEREOF FOR THE TREATMENT OF DIABETES
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Page/Page column 25-26, (2009/10/22)
The present invention relates to quinoxalinone derivatives of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as defined in claim 1, as insulin secretion stimulators. The invention also relates to the preparation and use of these quinoxalinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated. Other preferred compounds are compounds of general formula (I), wherein R1, R2, R3, R4, R5 and R6 can be optionally substituted by one or more groups selected from Z.
Improved synthesis of functionalized mesogenic 2,6-bisbenzimidazolylpyridine ligands
McKenzie, Blayne M.,Miller, Adriane K.,Wojtecki, Rudy J.,Johnson, J. Casey,Burke, Kelly A.,Tzeng, Karis A.,Mather, Patrick T.,Rowan, Stuart J.
, p. 8488 - 8495 (2008/12/20)
A versatile one-pot synthetic platform for the preparation of a range of functionalized 2,6-bisbenzimidazolylpyridine (Bip) derivatives is presented. This protocol significantly reduces the cost and time of previous synthetic routes, while facilitating sc
