502421-28-5Relevant articles and documents
Carbon-carbon bond construction at the 2-position of polysubstituted pyrimidinones
Zhang, Dawei,Sham, Kelvin,Cao, Guo-Qiang,Hungate, Randall,Dominguez, Celia
, p. 8901 - 8903 (2007/10/03)
A novel synthetic method to introduce a carbon-carbon bond at the 2-position of pyrimidinones via nucleophilic addition of Grignard reagents to 2-cyano pyrimidinones at ambient conditions is disclosed. This unique approach leads to the preparation of such