502640-59-7Relevant academic research and scientific papers
Substituent effect on the formation of helical to layered hydrogen bond networks in hydroxyl and carboxyl substituted 1-aryl-1H-1,2,3-triazoles
Sureshbabu, Bemineni,Venkatachalam, Ramkumar,Sankararaman, Sethuraman
, p. 6098 - 6106 (2014)
Six structurally related 1-aryl-1H-1,2,3-triazoles substituted with hydroxyl and carboxyl groups have been studied by single crystal X-ray crystallography. O-H...N and O-H...O hydrogen bond synthons play a predominant role in the crystal engineering of th
Bioisosteric Replacement of Amide Group with 1,2,3-Triazoles in Acetaminophen Addresses Reactive Oxygen Species-Mediated Hepatotoxic Insult in Wistar Albino Rats
Agrawal, Ramkishore,Das, Debashree,Gajbhiye, Asmita,Mishra, Shweta,Sahu, Adarsh,Sahu, Preeti,Sakthivel, Ayyamperumal
, (2020/02/04)
Acetaminophen (AP) is a popularly recommended over-the-counter analgesic-antipyretic in clinical use. However, the drug is handicapped by the occurrence of hepatotoxic insult following acute ingestion. Consequently, AP-induced hepatotoxicity is often impl
Synthesis of 1,2,3-triazole derived potential peptidomimetics
Dabak, Kadir,Akar, Ahmet
, p. 385 - 390 (2007/10/03)
In this study, synthesis of some new 1,2,3-triazole derived potential scaffold type peptidomimetics are described.
