50271-21-1

Basic information

• Product Name: 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl bromide
• Synonyms: 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl bromide
• CAS NO: 50271-21-1
• Molecular Weight: 525.353
• Mol File: 50271-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl bromide(50271-21-1)
• EPA Substance Registry System: 2,3,4-tri-O-benzoyl-β-D-xylopyranosyl bromide(50271-21-1)

Safety Data

• Hazardous Substances Data: 50271-21-1(Hazardous Substances Data)

Upstream product

• 7473-43-0 tetra-O-benzoyl-β-D-ribopyranose 
• 372515-38-3 1',2',3',4'-tetra-O-benzoyl-L-lyxopyranose 
• 10257-32-6 D-ribose 
• 909273-47-8 O²,O³,O⁴-Tribenzoyl-β-D-ribopyranose 

Downstream Products

• 13035-48-8 tri-O-benzoyl-α-D-ribopyranosyl bromide 
• 1239883-54-5 propargyl 2,3,4-tri-O-benzoyl-β-D-ribopyranoside 
• 1137149-66-6 oleanolic acid 2,3,4-tri-O-benzyl-β-D-xylopyranosyl ester 
• 950762-02-4 4-formylphenyl (2,3,4-tri-O-benzoyl)-β-D-ribopyranoside 
• 950762-01-3 4-formylphenyl 2,3,4-tri-O-benzoyl-β-D-xylopyranoside 
• 29581-29-1 O³-benzoyl-O¹,O²,O⁴-phenylmethanetriyl-α-D-ribopyranose 
• 32087-42-6 O³-acetyl-O¹,O²,O⁴-phenylmethanetriyl-α-D-ribopyranose 
• 34368-58-6 O¹,O²,O⁴-phenylmethanetriyl-α-D-ribopyranose 
• 13035-47-7 tri-O-benzoyl-α-D-ribopyranosyl chloride 
• 14218-06-5 tri-O-benzoyl-1,5-anhydro-ribitol 
• 909273-47-8 O²,O³,O⁴-Tribenzoyl-β-D-ribopyranose 
• 905918-15-2 (1'R,3'S)-2',2'-dichloro-3'-hydroxycyclobutyl 2,3,4-tri-O-benzoyl-β-D-ribopyranoside 
• 905918-07-2 vinyl 2,3,4-tri-O-benzoyl-β-D-ribopyranoside 
• 905918-23-2 formyl 2,3,4-tri-O-benzoyl-β-D-ribopyranoside 

Relevant articles and documents

Synthesis of Functionalized 2-(4-Hydroxyphenyl)-3-methylbenzofuran Allosteric Modulators of Hsp90 Activity

Hsp90 is a molecular chaperone that plays a pivotal role in the cell life cycle. ATP-regulated internal dynamics are critical to Hsp90 function and we recently demonstrated that these dynamics can be modulated in an allosteric fashion; the protein C-terminal domain (CTD) can be effectively targeted with a family of 2-phenyl-benzofuran derivatives. Here we describe the expansion of the initial library, reporting 28 new derivatives that explore the chemical space at opposite ends of the benzofuran scaffold. Interactions of the compounds with a full-length protein homolog were explored by Saturation Transfer Difference (STD) NMR spectroscopy. In this context we also report the interaction epitope of Novobiocin, a known CTD inhibitor.