50271-42-6

Basic information

• Product Name: 5,6-O-isopropylidene-D-isoascorbic acid
• Synonyms: 5,6-O-isopropylidene-D-isoascorbic acid
• CAS NO: 50271-42-6
• Molecular Weight: 216.191
• Mol File: 50271-42-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5,6-O-isopropylidene-D-isoascorbic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-O-isopropylidene-D-isoascorbic acid(50271-42-6)
• EPA Substance Registry System: 5,6-O-isopropylidene-D-isoascorbic acid(50271-42-6)

Safety Data

• Hazardous Substances Data: 50271-42-6(Hazardous Substances Data)

Upstream product

• 10504-35-5 D-ascorbic acid 
• 127392-14-7 (R)-3-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-5,10-dihydro-3H-2,4,11-trioxa-benzo[a]cyclopenta[e]cycloocten-1-one 
• 50-81-7 ascorbic acid 
• 67-64-1 acetone 

Downstream Products

• 86404-07-1 5,6-O-isopropylidene-3-O-benzylascorbic acid 
• 14200-03-4 3-O-benzoyl-5,6-O-isopropylidene-L-ascorbic acid 
• 117205-81-9 potassium (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 23313-12-4 Ascorbate-2-phosphate 
• 116565-57-2 2-O-(diphenylphosphinyl)-5,6-O-isopropylidene-L-ascorbic acid 
• 116565-54-9 3-O-(diphenylphosphinyl)-5,6-O-isopropylidene-L-ascorbic acid 
• 552887-06-6 methyl (2R,3R)-2-(3-bromobenzyloxy)-3,4-dihydroxy-3,4-O-isopropylidene-butyrate 
• 552887-04-4 methyl (2R,3R)-2-(4-bromobenzyloxy)-3,4-dihydroxy-3,4-O-isopropylidene-butyrate 
• 32233-44-6 2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acetaldehyde 
• 126946-54-1 ethyl (2R,3R)-3,4-O-isopropylidene-2-p-toluenesulfonyl-3,4-dihydroxybutanoate 
• 60456-21-5 methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 87604-49-7 (2R,3S)-3-O-benzyl-1,2-O-isopropylidenebutane-1,2,3-triol 
• 114185-11-4 (2R,3R)-3-O-benzoyl-1,2-isopropylidenebutane-1,2,3-triol 
• 114184-99-5 <4R-(R*,S*)>-4-<1,2-Bis(phenylmethoxy)ethyl>-2,2-dimethyl-1,3-dioxolan 

Relevant articles and documents

ASCORBIC ACID DERIVATIVES AND SKIN-WHITENING COSMETICS

It is an object to provide an L-ascorbic acid derivative which can keep the L-ascorbic acid stable to heat and light and thus has a long shelf life, which is high in permeability into the skin, which can be quickly hydrolyzed by phosphatase, an enzyme that is ubiquitous in vivo, and which exhibits physiological activities that are inherent to L-ascorbic acid and beneficial to health, a method for producing such an L-ascorbic acid derivative, and a skin-whitening cosmetic material. There is provided an ascorbic acid derivative comprising an L-ascorbic acid-2-phosphate ester or a salt thereof wherein the phosphate ester has a branched alkyl group, the L-ascorbic acid-2-phosphate ester being of formula [13]. The ascorbic acid derivative is produced by a method comprising reacting a branched alkanol with phosphorus oxychloride to synthesize monoalkyldichlorophosphate or dialkylmonochlorophosphate, reacting the thus obtained substance with 5,6-O-isopropylidene-L-ascorbic acid obtained by reacting L-ascorbic acid with acetone, and subjecting the thus obtained substance to acid hydrolysis. There is also provided a cosmetic material containing such an ascorbic acid derivative by 0.05 to 80 percent by weight. (wherein each of R1 and R2 is a hydrogen (H) atom or an alkyl group having branches and including 3 to 30 carbon atoms, but not both of R1 and R2 are hydrogen (H) atoms)