503-01-5 Usage
Originator
Octinum,Knoll,US,1948
Uses
Different sources of media describe the Uses of 503-01-5 differently. You can refer to the following data:
1. ctin (Knoll).
2. 6-Methylamino-2-methylheptene is an intermediate for the synthesis of Isometheptene Maleate (I821325), which belongs to a group of sympathomimetic amine and shows very little antihypertensive activity. Isometheptene Maleate is used as an antispasmodic drug.
Manufacturing Process
Methyl heptenone dissolved in 75% alcohol is reduced with activated
aluminum in the presence of methylamine to give isometheptene.
Therapeutic Function
Muscle relaxant
Check Digit Verification of cas no
The CAS Registry Mumber 503-01-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 503-01:
(5*5)+(4*0)+(3*3)+(2*0)+(1*1)=35
35 % 10 = 5
So 503-01-5 is a valid CAS Registry Number.
503-01-5Relevant articles and documents
Enabling New Modes of Reactivity via Constrictive Binding in a Supramolecular-Assembly-Catalyzed Aza-Prins Cyclization
Kaphan, David M.,Toste, F. Dean,Bergman, Robert G.,Raymond, Kenneth N.
supporting information, p. 9202 - 9205 (2015/08/18)
Supramolecular assembly 1 catalyzes a bimolecular aza-Prins cyclization featuring an unexpected transannular 1,5-hydride transfer. This reaction pathway, which is promoted by constrictive binding within the supramolecular cavity of 1, is kinetically disfavored in the absence of 1, as evidenced by the orthogonal reactivity observed in bulk solution. Mechanistic investigation through kinetic analysis and isotopic labeling studies indicates that the rate-limiting step of the transformation is the encapsulation of a transient iminium ion and supports the proposed 1,5-hydride transfer mechanism. This represents a rare example of such an extreme divergence of product selectivity observed within a catalytic metal-ligand supramolecular enzyme mimic.
